PMID- 9331571
OWN - NLM
STAT- MEDLINE
DCOM- 19971125
LR  - 20061115
IS  - 1045-2257 (Print)
IS  - 1045-2257 (Linking)
VI  - 20
IP  - 2
DP  - 1997 Oct
TI  - Breakpoints of 19q13 translocations of benign thyroid tumors map within a 400 
      kilobase region.
PG  - 201-3
AB  - Structural rearrangements involving the long arm of chromosome 19 characterize a 
      cytogenetic subgroup of benign thyroid tumors. To localize the breakpoint of the 
      19q13 aberrations, we have established three cell lines derived from benign 
      thyroid tumors showing translocations in this region. We have used these cell 
      lines and four additional primary tumors with 19q13 abnormalities for 
      fluorescence in situ hybridization (FISH) mapping studies with ten cosmid clones 
      located between the molecular markers POLD1 and TNNT1. The breakpoints of all 
      chromosome 19 abnormalities mapped within a 400 kb region.
FAU - Belge, G
AU  - Belge G
AD  - Center for Human Genetics and Genetic Counselling, University of Bremen, Germany.
FAU - Garcia, E
AU  - Garcia E
FAU - Rippe, V
AU  - Rippe V
FAU - Fusco, A
AU  - Fusco A
FAU - Bartnitzke, S
AU  - Bartnitzke S
FAU - Bullerdiek, J
AU  - Bullerdiek J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genes Chromosomes Cancer
JT  - Genes, chromosomes & cancer
JID - 9007329
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Adenoma/*genetics
MH  - Chromosome Breakage
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 19/*genetics
MH  - Genetic Markers
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Thyroid Neoplasms/*genetics
MH  - Translocation, Genetic
MH  - Tumor Cells, Cultured
EDAT- 1997/10/23 22:24
MHDA- 2000/06/20 09:00
CRDT- 1997/10/23 22:24
PHST- 1997/10/23 22:24 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1997/10/23 22:24 [entrez]
AID - 10.1002/(SICI)1098-2264(199710)20:2<201::AID-GCC11>3.0.CO;2-T [pii]
PST - ppublish
SO  - Genes Chromosomes Cancer. 1997 Oct;20(2):201-3.