PMID- 9352481 OWN - NLM STAT- MEDLINE DCOM- 19971124 LR - 20220210 IS - 1081-597X (Print) IS - 1081-597X (Linking) VI - 13 IP - 6 DP - 1997 Sep-Oct TI - Comparison of laser in situ keratomileusis and photorefractive keratectomy to correct myopia from -1.25 to -6.00 diopters. PG - 528-34 AB - BACKGROUND: We evaluated the safety and efficacy of laser in situ keratomileusis (LASIK) for the correction of low to moderate amounts of myopia (-1.25 to -6.00 D). METHODS: Photorefractive keratectomy (PRK) was performed on 432 eyes and LASIK on 137 eyes with a Chiron Keracor 116 excimer laser. Uncorrected and corrected visual acuity, corneal sensitivity, contrast sensitivity, and corneal topography were examined before and after surgery. RESULTS: One-year follow-up of 307 eyes in the PRK group and 103 eyes in the LASIK group was achieved. At 1 year, 83% (85 of 103) of LASIK eyes and 72% (221 of 307) of PRK eyes had an uncorrected visual acuity of 1.0 or better. Eighty-nine percent (92 of 103) of LASIK eyes and 83% (255 of 307) of PRK eyes had a refractive error within +/- 1.00 D of emmetropia; 71% (73 of 103) of LASIK eyes and 61% (188 of 307) of PRK eyes were within +/- 0.50 D of emmetropia. Contrast sensitivity and corneal sensitivity were reduced in both groups at the early postoperative stage but gradually returned to preoperative values; their recovery took about 3 months in LASIK eyes and 6 to 12 months in PRK eyes. CONCLUSION: LASIK is safe and more predictable than PRK to correct low to moderate amounts of myopia. Recovery from LASIK is faster than after PRK. FAU - Wang, Z AU - Wang Z AD - Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, Peoples Republic of China. gzstwang@public1.guangzhou.gd.cn FAU - Chen, J AU - Chen J FAU - Yang, B AU - Yang B LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Refract Surg JT - Journal of refractive surgery (Thorofare, N.J. : 1995) JID - 9505927 SB - IM MH - Contrast Sensitivity MH - Cornea/pathology/*surgery MH - Corneal Topography MH - Corneal Transplantation/methods MH - Follow-Up Studies MH - Humans MH - Laser Therapy/*methods MH - Lasers, Excimer MH - Myopia/*surgery MH - Photorefractive Keratectomy/*methods MH - Refraction, Ocular MH - Safety MH - Time Factors MH - Treatment Outcome EDAT- 1997/11/14 00:00 MHDA- 1997/11/14 00:01 CRDT- 1997/11/14 00:00 PHST- 1997/11/14 00:00 [pubmed] PHST- 1997/11/14 00:01 [medline] PHST- 1997/11/14 00:00 [entrez] AID - 10.3928/1081-597X-19970901-09 [doi] PST - ppublish SO - J Refract Surg. 1997 Sep-Oct;13(6):528-34. doi: 10.3928/1081-597X-19970901-09.