PMID- 9363498 OWN - NLM STAT- MEDLINE DCOM- 19971219 LR - 20190816 IS - 0167-5273 (Print) IS - 0167-5273 (Linking) VI - 62 IP - 1 DP - 1997 Oct 31 TI - Percutaneous transvenous mitral commissurotomy using an Inoue balloon in children with rheumatic mitral stenosis. PG - 19-22 AB - Percutaneous transvenous mitral commissurotomy (PTMC) using the Inoue technique was performed in 557 patients with rheumatic mitral stenosis. Of these, 107 were children aged 10-18 years (mean +/- SD 14.5 +/- 2.3). All patients were symptomatic New York Heart Association (NYHA) Class II (n = 78) and Class III (n = 29). All were in sinus rhythm. Following PTMC, the mitral valve area (MVA) increased from 0.73 +/- 0.18 to 1.7 +/- 0.53 cm2 (P < 0.001). There was a significant fall in mean transmitral gradient from 15.6 +/- 5.2 to 5.1 +/- 2.3 mmHg, and in mean pulmonary artery pressure from 41 +/- 15 to 28.4 +/- 10 (P < 0.001). Cardiac tamponade developed in one patient. One patient developed severe mitral regurgitation requiring emergency mitral valve replacement. Five patients (4.7%) developed moderate mitral regurgitation. There was no mortality or cerebral embolism in any of the children. Four patients (3.7%) had oximetry evidence of atrial septal defect. Mean mitral valve area and transmitral gradient at 14 months mean follow up was 1.68 +/- 0.4 cm2 and 6 +/- 3.5 mmHg, respectively, and were comparable to the immediate post-PTMC results. Two patients (1.8%) developed restenosis. The immediate haemodynamic results in children were compared to 450 adult patients who underwent PTMC in the same period. The outcome was similar in both groups. Children were found to have significantly higher pulmonary artery pressure compared to adults. We found that PTMC using an Inoue balloon is very effective and safe in children, and consider that it should be the procedure of choice for young patients with symptomatic rheumatic mitral stenosis. FAU - Joseph, P K AU - Joseph PK AD - Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala, India. FAU - Bhat, A AU - Bhat A FAU - Francis, B AU - Francis B FAU - Sivasankaran, S AU - Sivasankaran S FAU - Kumar, A AU - Kumar A FAU - Pillai, V R AU - Pillai VR FAU - Titus, T AU - Titus T FAU - Tharakan, J M AU - Tharakan JM FAU - Balakrishnan, K G AU - Balakrishnan KG LA - eng PT - Clinical Trial PT - Comparative Study PT - Journal Article PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM CIN - Int J Cardiol. 1998 Sep 1;66(1):97-8. PMID: 9781796 MH - Adolescent MH - Adult MH - *Balloon Occlusion MH - Catheterization/*instrumentation/methods MH - Child MH - Echocardiography MH - Female MH - Follow-Up Studies MH - Hemodynamics/physiology MH - Humans MH - Male MH - Mitral Valve Stenosis/diagnostic imaging/*surgery MH - Prognosis MH - Rheumatic Heart Disease/*surgery MH - Treatment Outcome EDAT- 1997/11/18 00:00 MHDA- 1997/11/18 00:01 CRDT- 1997/11/18 00:00 PHST- 1997/11/18 00:00 [pubmed] PHST- 1997/11/18 00:01 [medline] PHST- 1997/11/18 00:00 [entrez] AID - S0167527397001885 [pii] AID - 10.1016/s0167-5273(97)00188-5 [doi] PST - ppublish SO - Int J Cardiol. 1997 Oct 31;62(1):19-22. doi: 10.1016/s0167-5273(97)00188-5.