PMID- 9369925
OWN - NLM
STAT- MEDLINE
DCOM- 19971204
LR  - 20231112
IS  - 0910-5050 (Print)
IS  - 1876-4673 (Electronic)
IS  - 0910-5050 (Linking)
VI  - 88
IP  - 9
DP  - 1997 Sep
TI  - Assessment of preference for breast cancer chemoprevention in Japanese young 
      women.
PG  - 792-6
AB  - Pills containing estrogen and progesterone or gonadotropin releasing hormone 
      agonist have been considered valuable to prevent breast cancer. This study 
      assessed preference for the combination-type pill for preventing breast cancer, 
      to evaluate the hypothetical preventive effect of this agent among young Japanese 
      women. The standard gamble method was applied. Fifty-five college students and 44 
      nursing school students aged between 18 and 41 years were asked to decide the 
      probability of being affected by breast cancer at which they would start to take 
      this agent. Preference score was calculated by subtracting the probability given 
      by each respondent from 1, which corresponds to the value (utility) she allotted 
      to the agent. The means of preference score were 0.58, 0.48, 0.37, and 0.27 for 
      100, 75, 50, and 25% of efficacy levels of the agent, respectively. Preference 
      score was significantly lower in nursing school students and those whose 
      knowledge about hormones were relatively high. Score of Health Locus of Control 
      (HLC) was nonsignificantly negatively correlated with preference score at any 
      efficacy level. HLC score was significantly higher among those who refused the 
      agent with 50 and 25% efficacy levels at 100% level of breast cancer risk. The 
      data suggest that perceived risk of this agent was not negligibly small in this 
      population and school status, knowledge about hormones, and beliefs about health 
      would affect preference for the agent. Understanding of preference for 
      chemopreventive agents for breast cancer, especially those containing hormones, 
      is important to assess their potential as future preventive agents and is helpful 
      when planning a strategy of chemoprevention.
FAU - Nagata, C
AU  - Nagata C
AD  - Department of Public Health, Gifu University School of Medicine.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - Jpn J Cancer Res
JT  - Japanese journal of cancer research : Gann
JID - 8509412
RN  - 0 (Anticarcinogenic Agents)
RN  - 0 (Drug Combinations)
RN  - 0 (Estrogens)
RN  - 33515-09-2 (Gonadotropin-Releasing Hormone)
RN  - 4G7DS2Q64Y (Progesterone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Anticarcinogenic Agents/*therapeutic use
MH  - *Attitude to Health
MH  - Breast Neoplasms/epidemiology/*prevention & control
MH  - Chemoprevention
MH  - Consumer Behavior
MH  - Drug Combinations
MH  - Estrogens/therapeutic use
MH  - Female
MH  - Gonadotropin-Releasing Hormone/therapeutic use
MH  - Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - Internal-External Control
MH  - Japan
MH  - Progesterone/therapeutic use
MH  - Risk Factors
MH  - Students
MH  - Students, Nursing
MH  - Universities
PMC - PMC5921509
EDAT- 1997/11/25 00:00
MHDA- 1997/11/25 00:01
PMCR- 1997/09/01
CRDT- 1997/11/25 00:00
PHST- 1997/11/25 00:00 [pubmed]
PHST- 1997/11/25 00:01 [medline]
PHST- 1997/11/25 00:00 [entrez]
PHST- 1997/09/01 00:00 [pmc-release]
AID - S091050509785586X [pii]
AID - CAE792 [pii]
AID - 10.1111/j.1349-7006.1997.tb00453.x [doi]
PST - ppublish
SO  - Jpn J Cancer Res. 1997 Sep;88(9):792-6. doi: 10.1111/j.1349-7006.1997.tb00453.x.