PMID- 9387932
OWN - NLM
STAT- MEDLINE
DCOM- 19980206
LR  - 20191102
IS  - 0948-6143 (Print)
IS  - 0948-6143 (Linking)
VI  - 108
IP  - 4-5
DP  - 1997 Oct-Nov
TI  - Fluorescence in situ hybridization as a diagnostic tool in malignant lymphomas.
PG  - 391-402
AB  - Primary and secondary chromosomal abnormalities play an important role in the 
      characterization of biological, pathological, and clinical subgroups of malignant 
      lymphomas. The introduction of fluorescence in situ hybridization (FISH) and the 
      combination of immunophenotyping plus FISH to the diagnosis of lymphatic 
      neoplasms allows the fast and sensitive detection of specific chromosomal changes 
      and provides new insights into the genetic basis of lymphomagenesis. This article 
      reviews the possibilities and limitations of molecular cytogenetic techniques in 
      comparison to cytogenetic and molecular genetic methods and discusses their 
      clinicopathological impact for non-Hodgkin's lymphoma and Hodgkin's disease.
FAU - Siebert, R
AU  - Siebert R
AD  - Department of Human Genetics, University of Kiel, Germany.
FAU - Weber-Matthiesen, K
AU  - Weber-Matthiesen K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Germany
TA  - Histochem Cell Biol
JT  - Histochemistry and cell biology
JID - 9506663
SB  - IM
MH  - Chromosome Aberrations
MH  - Chromosome Deletion
MH  - Hodgkin Disease/*diagnosis/genetics
MH  - Humans
MH  - Immunophenotyping
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Lymphoma, Non-Hodgkin/*diagnosis/genetics
MH  - Translocation, Genetic
RF  - 80
EDAT- 1997/12/05 00:00
MHDA- 1997/12/05 00:01
CRDT- 1997/12/05 00:00
PHST- 1997/12/05 00:00 [pubmed]
PHST- 1997/12/05 00:01 [medline]
PHST- 1997/12/05 00:00 [entrez]
AID - 10.1007/s004180050180 [doi]
PST - ppublish
SO  - Histochem Cell Biol. 1997 Oct-Nov;108(4-5):391-402. doi: 10.1007/s004180050180.