PMID- 9389272 OWN - NLM STAT- MEDLINE DCOM- 19971217 LR - 20190515 IS - 0007-0912 (Print) IS - 0007-0912 (Linking) VI - 79 IP - 4 DP - 1997 Oct TI - Overestimation of low cardiac output measured by thermodilution. PG - 514-6 AB - We have investigated the influence of a cold water bolus (CWB) injection on overestimation of cardiac output (CO) in low CO states in anaesthetized dogs. CO was measured using three methods: (1) thermodilution (TD), (2) electromagnetic (EM) flow meter placed on the pulmonary artery and (3) transoesophageal echo-Doppler (OD) placed on the descending aorta. Measurements of CO were obtained before (steady state) and after induction of a low CO state with thiopentone 5 mg kg-1 i.v. After CWB injection, mean CO measured by EM and OD increased by 26% and 27%, respectively (P < 0.05) during steady state, and by 85% and 75% (P < 0.05) during the low CO state. This transient increase was produced by an increase in stroke volume, while heart rate did not change. Frank Starling's law may explain this variation by a sudden increase in preload produced by CWB injection. These results indicate that thermodilution overestimated CO during low CO states when CWB injection was used. FAU - Tournadre, J P AU - Tournadre JP AD - Critical Care Division, Hopital de l'Hotel-Dieu, Lyon, France. FAU - Chassard, D AU - Chassard D FAU - Muchada, R AU - Muchada R LA - eng PT - Journal Article PL - England TA - Br J Anaesth JT - British journal of anaesthesia JID - 0372541 SB - IM MH - Animals MH - Aorta, Thoracic/diagnostic imaging MH - Cardiac Output, Low/*diagnosis/diagnostic imaging MH - Cold Temperature MH - Dogs MH - Echocardiography, Doppler MH - Echocardiography, Transesophageal MH - Electromagnetic Phenomena MH - Hemorheology/instrumentation MH - Pulmonary Artery/physiopathology MH - *Thermodilution EDAT- 1997/12/06 00:00 MHDA- 1997/12/06 00:01 CRDT- 1997/12/06 00:00 PHST- 1997/12/06 00:00 [pubmed] PHST- 1997/12/06 00:01 [medline] PHST- 1997/12/06 00:00 [entrez] AID - S0007-0912(17)39828-8 [pii] AID - 10.1093/bja/79.4.514 [doi] PST - ppublish SO - Br J Anaesth. 1997 Oct;79(4):514-6. doi: 10.1093/bja/79.4.514.