PMID- 9405002
OWN - NLM
STAT- MEDLINE
DCOM- 19980204
LR  - 20190814
IS  - 0001-6314 (Print)
IS  - 0001-6314 (Linking)
VI  - 96
IP  - 5
DP  - 1997 Nov
TI  - Early CCT signs of supratentorial brain infarction: clinico-radiological 
      correlations.
PG  - 317-23
AB  - Early signs of brain infarction can be detected by modern CCT technology even 
      within the first 6 h after stroke. Little is known about the prognostic 
      significance of early infarction signs in CCT. We prospectively evaluated 
      clinical and CCT findings of 95 consecutive patients with an acute ischemia in 
      the territory of the middle cerebral artery. All patients were admitted to our 
      stroke unit within 6 h after stroke. In 55 patients CCT was performed within 3 h, 
      and in 40 cases between 3 and 6 h. In all patients the clinical findings were 
      assessed by the Scandinavian Stroke Scale (SSS). The disability due to stroke was 
      evaluated after 4 weeks by use of the modified Rankin Scale. We could demonstrate 
      the following early signs of cerebral infarction: focal hypodensity (23.2%), 
      obscuration of basal ganglia (12.6%), focal brain swelling (22.1%), hyperdense 
      middle cerebral artery sign (HMCA; 11.5%). In 3 patients early edema led to 
      ventricular compression, in 1 patient to midline shift. The occurrence of early 
      infarction signs did not depend on the etiology of ischemia but was significantly 
      associated with a severe neurological deficit at admission and an unfavourable 
      disability status 4 weeks after stroke. Focal brain swelling and HMCA were often 
      followed by extensive infarction lesions on the follow-up CCT. In conclusion, 
      early signs of hemispheric brain infarction visible on CCT scans performed within 
      6 h after stroke are correlated with severe stroke and an unfavourable functional 
      outcome. However, a substantial part of our patients had a benign course of the 
      disease in spite of early CCT pathology. Decisions on therapy in individual 
      patients therefore should not depend on early CCT findings exclusively.
FAU - Buttner, T
AU  - Buttner T
AD  - Department of Neurology, Ruhr University, St Josef-Hospital, Bochum, Germany.
FAU - Uffmann, M
AU  - Uffmann M
FAU - Gunes, N
AU  - Gunes N
FAU - Koster, O
AU  - Koster O
LA  - eng
PT  - Journal Article
PL  - Denmark
TA  - Acta Neurol Scand
JT  - Acta neurologica Scandinavica
JID - 0370336
SB  - IM
MH  - Acute Disease
MH  - Aged
MH  - Brain Edema/diagnostic imaging
MH  - Brain Mapping
MH  - Cerebral Arteries/diagnostic imaging
MH  - Cerebral Infarction/*diagnostic imaging
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neurologic Examination
MH  - Prognosis
MH  - Prospective Studies
MH  - Sensitivity and Specificity
MH  - *Tomography, X-Ray Computed
EDAT- 1997/12/24 00:00
MHDA- 1997/12/24 00:01
CRDT- 1997/12/24 00:00
PHST- 1997/12/24 00:00 [pubmed]
PHST- 1997/12/24 00:01 [medline]
PHST- 1997/12/24 00:00 [entrez]
AID - 10.1111/j.1600-0404.1997.tb00290.x [doi]
PST - ppublish
SO  - Acta Neurol Scand. 1997 Nov;96(5):317-23. doi: 
      10.1111/j.1600-0404.1997.tb00290.x.