PMID- 9406582
OWN - NLM
STAT- MEDLINE
DCOM- 19980108
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 100
IP  - 1
DP  - 1998 Jan 1
TI  - Radiation therapy for breast cancer and clonal chromosome translocations: a 
      fluorescence in situ hybridization study.
PG  - 57-62
AB  - The frequency of chromosomal translocations was analyzed in skin fibroblast cell 
      cultures derived from irradiated and nonirradiated skin biopsies from five cases 
      of breast adenocarcinoma in women, who had undergone radiotherapy after surgery. 
      The study was performed at the first annual check-up. Chromosomal in situ 
      suppression (CISS) hybridization was performed using metaphase nonisotopic 
      fluorescence in situ hybridization (FISH) with library probes specific for 
      chromosomes 1, 2, 3, 4, 5, 7, 8, 13, 19, and 20. The results showed that the 
      frequency of clonal translocations in metaphases obtained from irradiated areas 
      was significantly higher than in metaphases from the nonirradiated tissue 
      samples.
FAU - Larramendy, M L
AU  - Larramendy ML
AD  - Department of Medical Genetics, Haartman Institute, University of Helsinki, 
      Finland.
FAU - Majander, P
AU  - Majander P
FAU - Saarto, T
AU  - Saarto T
FAU - Tenhunen, M
AU  - Tenhunen M
FAU - Caballin, R
AU  - Caballin R
FAU - Elomaa, I
AU  - Elomaa I
FAU - Knuutila, S
AU  - Knuutila S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Aged
MH  - Breast Neoplasms/genetics/*radiotherapy
MH  - Female
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Middle Aged
MH  - *Translocation, Genetic
EDAT- 1997/12/24 00:00
MHDA- 1997/12/24 00:01
CRDT- 1997/12/24 00:00
PHST- 1997/12/24 00:00 [pubmed]
PHST- 1997/12/24 00:01 [medline]
PHST- 1997/12/24 00:00 [entrez]
AID - S0165460897000149 [pii]
AID - 10.1016/s0165-4608(97)00014-9 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1998 Jan 1;100(1):57-62. doi: 
      10.1016/s0165-4608(97)00014-9.