PMID- 9409457
OWN - NLM
STAT- MEDLINE
DCOM- 19980120
LR  - 20190905
IS  - 0022-3484 (Print)
IS  - 0022-3484 (Linking)
VI  - 32
IP  - 8
DP  - 1997 Nov
TI  - Six-year clinical evaluation of HTR synthetic bone grafts in human grade II molar 
      furcations.
PG  - 627-33
AB  - A biocompatible microporous composite of PMMA (poly-methyl-methacrylate), PHEMA 
      (poly-hydroxy-ethyl-methacrylate) and calcium hydroxide bone replacement graft 
      material (Bioplant HTR Synthetic Bone) was evaluated in 16 maxillary molar and 10 
      mandibular molar Grade II furcations in 13 patients. Following initial 
      preparation, full thickness flaps were raised to gain access to the furcations; 
      mechanical hand and ultrasonic root and defect debridement and chemical 
      tetracycline root preparation were performed; furcation and adjacent osseous 
      defects in each patient were grafted with HTR Synthetic Bone; and the host flaps 
      replaced or slightly coronally positioned. Weekly, then monthly deplaquing was 
      performed until surgical re-entry at 6-12 months. Patients were then followed on 
      approximate 3-month recalls for > or = 6 yr. Evaluation of the primary clinical 
      outcome of furcation grade change showed that in the maxilla 5/16 furcations were 
      clinically closed, 9/16 were Grade I, and 2/16 remained Grade II; while in the 
      mandible 3/10 were clinically closed, 5/10 were Grade I, and 2/10 remained Grade 
      II. Other significant clinical changes included decrease in mean horizontal 
      furcation probing attachment level from 4.4 mm at surgery to 2.2 mm at re-entry 
      to 2.0 mm at 6 yr, decrease in probing pocket depth from 5.4 mm at surgery to 3.0 
      mm at re-entry to 3.2 mm at 6 yr, and improvement in vertical clinical probing 
      attachment level from 5.4 mm at surgery to 4.2 mm at re-entry to 4.1 mm at 6 yr 
      (all p < 0.05 from surgery to re-entry and surgery to 6 yr, n.s. from re-entry to 
      6 yr via ANOVA). These favorable results with HTR polymer are similar to several 
      reports with other graft materials and with GTR barriers, and suggest that HTR 
      polymer may have a beneficial effect in the clinical management of Grade II molar 
      furcations.
FAU - Yukna, R A
AU  - Yukna RA
AD  - Louisiana State University School of Dentistry, New Orleans, USA.
FAU - Yukna, C N
AU  - Yukna CN
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Periodontal Res
JT  - Journal of periodontal research
JID - 0055107
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Biocompatible Materials)
RN  - 0 (Bone Substitutes)
RN  - 0 (Composite Resins)
RN  - 0 (Methylmethacrylates)
RN  - 25249-16-5 (Polyhydroxyethyl Methacrylate)
RN  - 26355-01-1 (HTR composite)
RN  - F8VB5M810T (Tetracycline)
SB  - IM
MH  - Adult
MH  - Alveoloplasty/methods
MH  - Analysis of Variance
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Biocompatible Materials/*therapeutic use
MH  - Bone Substitutes/*therapeutic use
MH  - Composite Resins/*therapeutic use
MH  - Debridement
MH  - Dental Plaque/prevention & control
MH  - Evaluation Studies as Topic
MH  - Female
MH  - Follow-Up Studies
MH  - Furcation Defects/classification/*surgery
MH  - Humans
MH  - Male
MH  - Mandible
MH  - Maxilla
MH  - Methylmethacrylates/*therapeutic use
MH  - Middle Aged
MH  - Molar/*surgery
MH  - Periodontal Attachment Loss/surgery
MH  - Periodontal Pocket/surgery
MH  - Polyhydroxyethyl Methacrylate/*therapeutic use
MH  - Reoperation
MH  - Root Planing
MH  - Surgical Flaps
MH  - Tetracycline/therapeutic use
MH  - Treatment Outcome
MH  - Ultrasonic Therapy
EDAT- 1997/12/31 00:00
MHDA- 1997/12/31 00:01
CRDT- 1997/12/31 00:00
PHST- 1997/12/31 00:00 [pubmed]
PHST- 1997/12/31 00:01 [medline]
PHST- 1997/12/31 00:00 [entrez]
AID - 10.1111/j.1600-0765.1997.tb00572.x [doi]
PST - ppublish
SO  - J Periodontal Res. 1997 Nov;32(8):627-33. doi: 
      10.1111/j.1600-0765.1997.tb00572.x.