PMID- 9413297
OWN - NLM
STAT- MEDLINE
DCOM- 19980114
LR  - 20190516
IS  - 0025-6196 (Print)
IS  - 0025-6196 (Linking)
VI  - 72
IP  - 12
DP  - 1997 Dec
TI  - Intravenous immunoglobulin-induced lichenoid dermatitis: a unique adverse 
      reaction.
PG  - 1151-2
AB  - Intravenous immunoglobulin (IVIG) therapy has been used to treat various 
      diseases. Generalized allergic reactions (types I, II, and III) to IVIG are 
      uncommon and are usually related to the rate of infusion. Cutaneous reactions 
      have been anecdotally described. Herein we describe a 73-year-old man with 
      Sjogren's syndrome who had development of a lichenoid cutaneous eruption after 
      administration of IVIG therapy. CD3 immunostaining demonstrated the overwhelming 
      presence of T lymphocytes within a lesional skin biopsy specimen, and thus we 
      present an alternative cell-mediated immune mechanism (type IV) by which allergic 
      reactions to IVIG may occur.
FAU - Yockey, S M
AU  - Yockey SM
AD  - Department of Dermatology, Mayo Clinic Rochester, Minnesota 55905, USA.
FAU - Ahmed, I
AU  - Ahmed I
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Mayo Clin Proc
JT  - Mayo Clinic proceedings
JID - 0405543
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Aged
MH  - Dermatitis/*etiology/pathology
MH  - Humans
MH  - Immunoglobulins, Intravenous/*adverse effects
MH  - Lichenoid Eruptions/*etiology/pathology
MH  - Male
MH  - Sjogren's Syndrome/therapy
EDAT- 1997/12/31 00:00
MHDA- 1997/12/31 00:01
CRDT- 1997/12/31 00:00
PHST- 1997/12/31 00:00 [pubmed]
PHST- 1997/12/31 00:01 [medline]
PHST- 1997/12/31 00:00 [entrez]
AID - S0025-6196(11)63680-X [pii]
AID - 10.4065/72.12.1151 [doi]
PST - ppublish
SO  - Mayo Clin Proc. 1997 Dec;72(12):1151-2. doi: 10.4065/72.12.1151.