PMID- 9421197
OWN - NLM
STAT- MEDLINE
DCOM- 19980115
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1349
IP  - 1
DP  - 1997 Nov 8
TI  - A novel 15-hydroxyeicosatrienoic acid-substituted diacylglycerol (15-HETrE-DAG) 
      selectively inhibits epidermal protein kinase C-beta.
PG  - 67-71
AB  - Diacylglycerol containing 15-hydroxyeicosatrienoic acid (15-HETrE-DAG) was 
      biosynthesized and examined for modulation of epidermal protein kinase C (PKC) 
      activity. 15-HETrE-DAG competitively inhibited diolein-activated total PKC 
      activity in a dose-dependent manner and further, selectively inhibited epidermal 
      PKC-beta activity.
FAU - Cho, Y
AU  - Cho Y
AD  - Institute of Human Nutrition, Columbia University, New York, NY 10032, USA.
FAU - Ziboh, V A
AU  - Ziboh VA
LA  - eng
GR  - R01-AM-30679/AM/NIADDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Diglycerides)
RN  - 0 (Enzyme Inhibitors)
RN  - 0 (Hydroxyeicosatetraenoic Acids)
RN  - 0 (Isoenzymes)
RN  - 82451-61-4 (15-hydroxyeicosatrienoic acid)
RN  - EC 2.7.11.13 (Protein Kinase C)
SB  - IM
MH  - Animals
MH  - Diglycerides/*pharmacology
MH  - Dose-Response Relationship, Drug
MH  - Enzyme Inhibitors/*pharmacology
MH  - Epidermis/*enzymology
MH  - Guinea Pigs
MH  - Hydroxyeicosatetraenoic Acids/*pharmacology
MH  - Isoenzymes/*antagonists & inhibitors
MH  - Protein Kinase C/*antagonists & inhibitors
EDAT- 1998/01/08 00:00
MHDA- 1998/01/08 00:01
CRDT- 1998/01/08 00:00
PHST- 1998/01/08 00:00 [pubmed]
PHST- 1998/01/08 00:01 [medline]
PHST- 1998/01/08 00:00 [entrez]
AID - S0005-2760(97)00144-6 [pii]
AID - 10.1016/s0005-2760(97)00144-6 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1997 Nov 8;1349(1):67-71. doi: 
      10.1016/s0005-2760(97)00144-6.