PMID- 9427039
OWN - NLM
STAT- MEDLINE
DCOM- 19980305
LR  - 20041117
IS  - 0258-851X (Print)
IS  - 0258-851X (Linking)
VI  - 11
IP  - 5
DP  - 1997 Sep-Oct
TI  - Longitudinal follow-up of two AIDS patients for active human herpesvirus-6 
      (HHV-6) infection.
PG  - 383-6
AB  - Because of the demonstrated presence of Human Herpesvirus-6 (HHV-6) in various 
      tissues and organs of HIV-1 infected AIDS patients, and its implication in the 
      pathogenesis of AIDS, we followed two AIDS patients for active HHV-6 infection 
      for two years. Evidence of active HHV-6 infection was demonstrated by 
      immunovirologic assays in both patients; however, the profile of infection in the 
      two patients varied. One patient showed appearance and disappearance of HHV-6, 
      indicating virus reactivation, whereas the other patient showed chronic or 
      persistent HHV-6 infection. Both patients' peripheral blood mononuclear cells 
      (PBMC) contained HIV-1 when their CD4 cell count was approximately 200 mm3. No 
      active HHV-6 was demonstrated in a healthy donor, who was used as a control for 
      this study.
FAU - Ablashi, D V
AU  - Ablashi DV
AD  - Advanced Biotechnologies Inc., Columbia, MD 21046, USA.
FAU - Chatlynne, L G
AU  - Chatlynne LG
FAU - Whitman, J E Jr
AU  - Whitman JE Jr
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - In Vivo
JT  - In vivo (Athens, Greece)
JID - 8806809
RN  - 0 (Antibodies, Viral)
RN  - 0 (Antigens, Viral)
RN  - 0 (DNA, Viral)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Viral Proteins)
RN  - 0 (p38 protein, Human herpesvirus 6)
RN  - 138415-18-6 (p41 protein, Human herpesvirus 6)
SB  - IM
MH  - Acquired Immunodeficiency Syndrome/blood/*complications/immunology
MH  - Adult
MH  - Antibodies, Viral/blood
MH  - Antigens, Viral/immunology
MH  - DNA, Viral/blood
MH  - DNA-Binding Proteins/immunology
MH  - Follow-Up Studies
MH  - Herpesviridae Infections/blood/*complications/immunology
MH  - *Herpesvirus 6, Human/genetics/immunology/isolation & purification
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Viral Proteins/immunology
EDAT- 1998/01/14 03:34
MHDA- 2001/03/28 10:01
CRDT- 1998/01/14 03:34
PHST- 1998/01/14 03:34 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1998/01/14 03:34 [entrez]
PST - ppublish
SO  - In Vivo. 1997 Sep-Oct;11(5):383-6.