PMID- 943140
OWN - NLM
STAT- MEDLINE
DCOM- 19760423
LR  - 20190626
IS  - 0002-9343 (Print)
IS  - 0002-9343 (Linking)
VI  - 60
IP  - 1
DP  - 1976 Jan
TI  - Pigeons breeders' disease. I. Serum immunoglobulin concentrations; IgG, IgM, IgA 
      and IgE antibodies against pigeon serum.
PG  - 144-51
AB  - The clinical course of a patient with severe acute and chronic hypersensitivity 
      pneumonitis of the pigeon breeders' disease (PBD) type was evaluated. A 
      significant remission of symptomatic, roentgenographic and pulmonary function 
      abnormalities occurred after cessation of exposure to antigen. Immunoglobulin G 
      (IgG), A (IgA) and M (IgM) antibody activity against pigeon serum was 
      demonstrated in the patient's serum by a solid phase radioimmunoassay (RIA) 
      technic. The levels of these antibodies fell subsequent to elimination of antigen 
      inhalation. The RIA technic was used to demonstrate IgG, IgA and IgM antibody 
      activity in single serum samples of four other patients with PBD, and this 
      technic may have diagnostic value. Although no immunoglobulin E (IgE) antibody 
      was demonstrable by RIA, a heat-liable, reaginic antibody was also detectable in 
      the serum of the primary case. In addition, Arthus type cutaneous reactivity was 
      passively transferred to the skin of a volunteer subject using heated serum from 
      a patient with PBD.
FAU - Patterson, R
AU  - Patterson R
FAU - Schatz, M
AU  - Schatz M
FAU - Fink, J N
AU  - Fink JN
FAU - DeSwarte, R S
AU  - DeSwarte RS
FAU - Roberts, M
AU  - Roberts M
FAU - Cugell, D
AU  - Cugell D
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Med
JT  - The American journal of medicine
JID - 0267200
RN  - 0 (Antigens)
RN  - 0 (Immunoglobulin A)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulin M)
RN  - 0 (Immunoglobulins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Aged
MH  - Animals
MH  - Antibody Formation
MH  - Antigens
MH  - Columbidae/*immunology
MH  - Farmer's Lung/*immunology
MH  - Humans
MH  - Immunization, Passive
MH  - Immunoglobulin A/analysis
MH  - Immunoglobulin E/analysis
MH  - Immunoglobulin G/analysis
MH  - Immunoglobulin M/analysis
MH  - Immunoglobulins/*analysis
MH  - Male
EDAT- 1976/01/01 00:00
MHDA- 1976/01/01 00:01
CRDT- 1976/01/01 00:00
PHST- 1976/01/01 00:00 [pubmed]
PHST- 1976/01/01 00:01 [medline]
PHST- 1976/01/01 00:00 [entrez]
AID - 0002-9343(76)90543-X [pii]
AID - 10.1016/0002-9343(76)90543-x [doi]
PST - ppublish
SO  - Am J Med. 1976 Jan;60(1):144-51. doi: 10.1016/0002-9343(76)90543-x.