PMID- 9435645
OWN - NLM
STAT- MEDLINE
DCOM- 19980209
LR  - 20190510
IS  - 0002-9513 (Print)
IS  - 0002-9513 (Linking)
VI  - 273
IP  - 6
DP  - 1997 Dec
TI  - Meal pattern analysis to investigate the satiating potential of fat, 
      carbohydrate, and protein in rats.
PG  - R1916-22
LID - 10.1152/ajpregu.1997.273.6.R1916 [doi]
AB  - We examined meal patterns after isocaloric duodenal infusions of fat, 
      carbohydrate (CHO), and protein by measuring meal size, intermeal interval (IMI) 
      and total food intake (TFI). Wistar rats were adapted to normal feeding 6 h/day, 
      with continuous computer monitoring of feeding patterns. One of five solutions 
      (10 ml of 1 kcal/ml at 0.45 ml/min; 0, 20, 50, 80, or 100% of energy from fat) or 
      saline (control) was infused 10 min after initiation of eating. Separate rats 
      received casein or casein hydrolysate at 18.5 or 37% energy. Equivalent energy 
      loads varying in fat, CHO, and protein content compared with saline resulted in 
      similar reductions in first meal intakes. The second meal did not differ among 
      fat and CHO treatments including saline; however, infusion with a 
      protein-containing solution increased the size of meal 2. The IMI was doubled by 
      protein infusion independently of dose or source but extended dose dependently by 
      fat. TFI was lower after high fat and higher after protein than after saline 
      infusion. The results indicate that the concentrations of fat, CHO, and protein 
      differentially affect the qualitative and quantitative aspects of feeding in 
      rats.
FAU - Burton-Freeman, B
AU  - Burton-Freeman B
AD  - Department of Nutrition, School of Veterinary Medicine, University of California, 
      Davis 95616, USA.
FAU - Gietzen, D W
AU  - Gietzen DW
FAU - Schneeman, B O
AU  - Schneeman BO
LA  - eng
GR  - DK-35747/DK/NIDDK NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Physiol
JT  - The American journal of physiology
JID - 0370511
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
SB  - IM
MH  - Animals
MH  - *Dietary Carbohydrates
MH  - *Dietary Fats
MH  - *Dietary Proteins
MH  - Duodenum/*physiology
MH  - Energy Intake
MH  - Energy Metabolism
MH  - Enteral Nutrition
MH  - *Feeding Behavior
MH  - Male
MH  - Rats
MH  - Rats, Wistar
MH  - Satiety Response/*physiology
MH  - Time Factors
EDAT- 1998/01/22 00:00
MHDA- 1998/01/22 00:01
CRDT- 1998/01/22 00:00
PHST- 1998/01/22 00:00 [pubmed]
PHST- 1998/01/22 00:01 [medline]
PHST- 1998/01/22 00:00 [entrez]
AID - 10.1152/ajpregu.1997.273.6.R1916 [doi]
PST - ppublish
SO  - Am J Physiol. 1997 Dec;273(6):R1916-22. doi: 10.1152/ajpregu.1997.273.6.R1916.