PMID- 9444919
OWN - NLM
STAT- MEDLINE
DCOM- 19980212
LR  - 20161013
IS  - 0929-6646 (Print)
IS  - 0929-6646 (Linking)
VI  - 96
IP  - 12
DP  - 1997 Dec
TI  - Comparison of major aeroallergens in Taipei and Kin-Men.
PG  - 985-9
AB  - Ragweed pollen is an important aeroallergen in the USA, however, its role in the 
      pathogenesis of allergic airway diseases in Taiwan has not been reported. 
      Recently, a dramatic increase in patients with allergic rhinitis was noted in 
      Kin-Men. Most patients had characteristic seasonal variation with the symptoms 
      waxing in August and waning in November, which correlated with the pollen season 
      of ragweed. The aim of this study was to clarify the role of ragweed pollen in 
      the pathogenesis of allergic airway disease in Taipei and Kin-Men. Ragweed pollen 
      from Kin-Men was collected, extracted, and resuspended in phosphate-buffered 
      saline for a skin prick test. Greer ragweed pollen extract was used as a control. 
      Serum from patients with a positive skin test was investigated for the ragweed 
      pollen-specific immunoglobulin E (IgE). The IgE-binding components in the ragweed 
      pollen were determined using immunoblot analysis. Of 101 patients from Kin-Men, 
      79 responded to ragweed. Only eight of 117 patients from Taipei responded to the 
      same allergen. The titers of ragweed-specific IgE antibodies in the sera from 
      Kin-Men were much higher than in the sera from Taipei. The response rate to the 
      most common indoor allergen, Dermatophagoides pteronyssinus, was much lower in 
      Kin-Men than in Taipei (25.7% and 90.6%, respectively). Thus, there were 
      different aeroallergens in Kin-Men and Taipei. Having what was in both cases a 
      Chinese population affected by different allergens indicates that environmental 
      allergens may play an important role in the pathogenesis of allergic airway 
      diseases. These results may also serve as a reference for the prophylaxis of 
      allergic rhinitis in Kin-Men.
FAU - Tsai, J J
AU  - Tsai JJ
AD  - Section of Allergy and Clinical Immunology, Cathay General Hospital-Taipei, 
      Taiwan.
FAU - Kao, M H
AU  - Kao MH
FAU - Huang, S L
AU  - Huang SL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Singapore
TA  - J Formos Med Assoc
JT  - Journal of the Formosan Medical Association = Taiwan yi zhi
JID - 9214933
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Allergens/*analysis
MH  - Child
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Male
MH  - Middle Aged
MH  - Pollen/*immunology
MH  - Skin Tests
MH  - Taiwan
EDAT- 1998/01/28 00:00
MHDA- 1998/01/28 00:01
CRDT- 1998/01/28 00:00
PHST- 1998/01/28 00:00 [pubmed]
PHST- 1998/01/28 00:01 [medline]
PHST- 1998/01/28 00:00 [entrez]
PST - ppublish
SO  - J Formos Med Assoc. 1997 Dec;96(12):985-9.