PMID- 9451953
OWN - NLM
STAT- MEDLINE
DCOM- 19980223
LR  - 20191102
IS  - 0967-3849 (Print)
IS  - 0967-3849 (Linking)
VI  - 5
IP  - 8
DP  - 1997 Dec
TI  - Part of the RBM gene cluster is located distally to the DAZ gene cluster in human 
      Yq11.23.
PG  - 537-40
AB  - Normal human Y and inverted Y chromosomes were chosen for physical fluorescence 
      in situ hybridization (FISH) mapping of RBM and DAZ probes for the relative 
      positioning of the RBM and DAZ gene clusters in interval 6 of the human Y 
      chromosome. The inversion breakpoint in Yq11.23 turned out to be distal to the 
      DAZ gene cluster, as the entire DAZ signal appears in the short arm of the inv(Y) 
      chromosome. On the contrary, this inversion breakpoint in Yq11.23 divides the RBM 
      signal cluster, leaving a weaker signal on the long arm while bringing the main 
      RBM signal to the short arm of the inv(Y) chromosome. Thus, it can be concluded 
      that, in contrast to previous claims, part of the RBM gene cluster is located 
      distally to the DAZ gene cluster in deletion interval 6 of the human Y 
      chromosome.
FAU - Pasantes, J J
AU  - Pasantes JJ
AD  - Institute of Human Genetics and Anthropology, University of Freiburg, Germany.
FAU - Rottger, S
AU  - Rottger S
FAU - Schempp, W
AU  - Schempp W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Chromosome Res
JT  - Chromosome research : an international journal on the molecular, supramolecular 
      and evolutionary aspects of chromosome biology
JID - 9313452
RN  - 0 (DAZ1 protein, human)
RN  - 0 (DNA Probes)
RN  - 0 (Deleted in Azoospermia 1 Protein)
RN  - 0 (Nuclear Proteins)
RN  - 0 (RBMY1A1 protein, human)
RN  - 0 (RNA-Binding Proteins)
SB  - IM
MH  - Chromosome Inversion
MH  - Chromosome Mapping/*methods
MH  - DNA Probes
MH  - Deleted in Azoospermia 1 Protein
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/methods
MH  - Male
MH  - Multigene Family/*genetics
MH  - Nuclear Proteins
MH  - RNA-Binding Proteins/*genetics
MH  - Y Chromosome/*genetics
EDAT- 1998/02/06 00:00
MHDA- 1998/02/06 00:01
CRDT- 1998/02/06 00:00
PHST- 1998/02/06 00:00 [pubmed]
PHST- 1998/02/06 00:01 [medline]
PHST- 1998/02/06 00:00 [entrez]
AID - 10.1023/a:1008850819150 [doi]
PST - ppublish
SO  - Chromosome Res. 1997 Dec;5(8):537-40. doi: 10.1023/a:1008850819150.