PMID- 9460492
OWN - NLM
STAT- MEDLINE
DCOM- 19980304
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 101
IP  - 1
DP  - 1998 Feb
TI  - Cytogenetic and fluorescence in situ hybridization analyses of hematologic 
      malignancies in Korea.
PG  - 1-6
AB  - Cytogenetic analysis was performed in 86 cases of hematologic malignancy, using 
      conventional cytogenetic analysis and fluorescence in situ hybridization (FISH) 
      analysis at two university hospitals in Korea between 1993 and 1995. In addition 
      to well-known anomalies, some unusual abnormalities were found, such as t(17;22), 
      trisomy 9 combined with t(14;17), (2;7) and Philadelphia chromosome in CML; 
      t(1;12), t(11;22), t(9;17), and t(12;21) in AML; trisomy 11 in MDS; t(2;9) and 
      complex t(8;8;13;14) in ALL. The results of FISH analysis in interphase nuclei 
      using a translocation probe for CML and APL showed more than 85% positive cells 
      in CML, and 75% positive cells in APL.
FAU - Koo, S H
AU  - Koo SH
AD  - Department of Clinical Pathology, ChungNam National University Hospital, Dae Jon, 
      South Korea.
FAU - Kwon, G C
AU  - Kwon GC
FAU - Chun, H J
AU  - Chun HJ
FAU - Park, J W
AU  - Park JW
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - EC 2.7.10.2 (Fusion Proteins, bcr-abl)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bone Marrow Cells/pathology
MH  - Chromosome Aberrations/pathology
MH  - Chromosome Disorders
MH  - Female
MH  - Fusion Proteins, bcr-abl/genetics
MH  - Hematologic Neoplasms/*genetics/pathology
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Korea
MH  - Leukemia, Lymphoid/genetics/pathology
MH  - Leukemia, Myeloid/genetics/pathology
MH  - Male
MH  - Middle Aged
MH  - Translocation, Genetic
EDAT- 1998/02/14 00:00
MHDA- 1998/02/14 00:01
CRDT- 1998/02/14 00:00
PHST- 1998/02/14 00:00 [pubmed]
PHST- 1998/02/14 00:01 [medline]
PHST- 1998/02/14 00:00 [entrez]
AID - S0165460897003579 [pii]
AID - 10.1016/s0165-4608(97)00357-9 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1998 Feb;101(1):1-6. doi: 10.1016/s0165-4608(97)00357-9.