PMID- 9465674 OWN - NLM STAT- MEDLINE DCOM- 19980421 LR - 20111117 IS - 0047-1852 (Print) IS - 0047-1852 (Linking) VI - 56 IP - 1 DP - 1998 Jan TI - [Laboratory diagnosis of cytomegalovirus, HHV-6 and HHV-7 infectious diseases]. PG - 109-14 AB - Cytomegalovirus, human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) are members of subfamily Betaherpesvirinae of family Herpesviridae. After infection, these betaherpesviruses persistent for the rest of life. Those viruses are occasionally reactivated and shed either with or without clinical symptoms. The laboratory diagnosis of the viral infections is established by the following methods: (1) isolation of the virus from specimens; (2) detection of virus antigens, and/or viral nucleic acids; and (3) detection of seroconversion or a significant rise in antibody titer. Accurate and rapid laboratory diagnosis of the viral diseases is prerequisite to effective antiviral chemotherapy. Especially, it is most important to distinguish viral diseases to be treated from mere viral infections. FAU - Minamishima, Y AU - Minamishima Y AD - Department of Microbiology, Miyazaki Medical College. FAU - Minematsu, T AU - Minematsu T LA - jpn PT - English Abstract PT - Journal Article PT - Review PL - Japan TA - Nihon Rinsho JT - Nihon rinsho. Japanese journal of clinical medicine JID - 0420546 RN - 0 (Antibodies, Viral) RN - 0 (Antigens, Viral) SB - IM MH - Antibodies, Viral/analysis MH - Antigens, Viral/analysis MH - *Clinical Laboratory Techniques MH - Cytomegalovirus Infections/*diagnosis/virology MH - Diagnosis, Differential MH - Herpesviridae Infections/*diagnosis/virology MH - Herpesvirus 6, Human/immunology/isolation & purification MH - Herpesvirus 7, Human/immunology/isolation & purification MH - Humans MH - Immunoenzyme Techniques MH - Polymerase Chain Reaction MH - Serologic Tests RF - 12 EDAT- 1998/02/18 00:00 MHDA- 1998/02/18 00:01 CRDT- 1998/02/18 00:00 PHST- 1998/02/18 00:00 [pubmed] PHST- 1998/02/18 00:01 [medline] PHST- 1998/02/18 00:00 [entrez] PST - ppublish SO - Nihon Rinsho. 1998 Jan;56(1):109-14.