PMID- 9465903
OWN - NLM
STAT- MEDLINE
DCOM- 19980304
LR  - 20180214
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 78
IP  - 3-4
DP  - 1997
TI  - Localization by fluorescence in situ hybridization (FISH) of human mitochondrial 
      polymerase gamma (POLG) to human chromosome band 15q24-->q26, and of mouse 
      mitochondrial polymerase gamma (Polg) to mouse chromosome band 7E, with 
      confirmation by direct sequence analysis of bacterial artificial chromosomes 
      (BACs).
PG  - 281-4
AB  - Cloned cDNAs for the human mitochondrial DNA polymerase gamma (POLG) were 
      identified by homology with the yeast mitochondrial DNA polymerase catalytic 
      subunit (MIP). Fluorescence in situ hybridization (FISH) of human and mouse 
      bacterial artificial chromosomes (BACs), hybridized by radioactively labeled POLG 
      cDNAs, mapped to human chromosome band 15q24-->q26, as well as to mouse 
      chromosome band 7E. Direct sequencing of the BAC DNA without subcloning confirmed 
      the presence of both human POLG and mouse mitochondrial DNA polymerase gamma 
      (Polg) in the respective BACs.
FAU - Zullo, S J
AU  - Zullo SJ
AD  - Laboratory of Biochemical Genetics, National Institute of Mental Health, National 
      Institutes of Health, Bethesda, MD 20892, USA. zullo@helix.nih.gov
FAU - Butler, L
AU  - Butler L
FAU - Zahorchak, R J
AU  - Zahorchak RJ
FAU - Macville, M
AU  - Macville M
FAU - Wilkes, C
AU  - Wilkes C
FAU - Merril, C R
AU  - Merril CR
LA  - eng
SI  - GENBANK/AF019118
SI  - GENBANK/AF019119
SI  - GENBANK/AF019120
SI  - GENBANK/AF019121
SI  - GENBANK/AF019122
SI  - GENBANK/AF019123
SI  - GENBANK/AF019124
SI  - GENBANK/AF019125
SI  - GENBANK/AF019126
SI  - GENBANK/AF019127
SI  - GENBANK/AF019128
SI  - GENBANK/AF019129
SI  - GENBANK/AF019130
SI  - GENBANK/AF019131
SI  - GENBANK/AF019132
SI  - GENBANK/AF019133
SI  - GENBANK/AF019134
PT  - Comparative Study
PT  - Journal Article
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
RN  - EC 2.7.7.7 (DNA Polymerase gamma)
RN  - EC 2.7.7.7 (DNA-Directed DNA Polymerase)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - *Chromosomes, Bacterial
MH  - *Chromosomes, Human, Pair 15
MH  - Cloning, Molecular/methods
MH  - DNA Polymerase gamma
MH  - DNA-Directed DNA Polymerase/*genetics
MH  - *Gene Transfer Techniques
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Mice
MH  - Mitochondria/enzymology/*genetics
MH  - Molecular Sequence Data
MH  - Sequence Analysis, DNA
MH  - Species Specificity
EDAT- 1997/01/01 00:00
MHDA- 1998/02/18 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1998/02/18 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - 10.1159/000134672 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1997;78(3-4):281-4. doi: 10.1159/000134672.