PMID- 9496741
OWN - NLM
STAT- MEDLINE
DCOM- 19980501
LR  - 20180213
IS  - 1660-8151 (Print)
IS  - 1660-8151 (Linking)
VI  - 78
IP  - 2
DP  - 1998
TI  - A case of chronic graft-versus-host disease following living-related donor kidney 
      transplantation.
PG  - 215-7
AB  - A 25-year-old man with a 2.5-year history of maintenance hemodialysis underwent a 
      living-related donor (father) kidney transplantation. He was free from acute 
      rejection, but 8 months after the kidney transplantation, he complained of 
      malaise and fever which were accompanied by eruptions on the face, fingers, and 
      hips which resembled symptoms seen in patients suffering from systemic 
      vasculitis. Skin biopsy findings were compatible with those of chronic 
      graft-versus-host disease (GVHD). The human leukocyte antigen (HLA) family study 
      disclosed that the donor's HLA haplotype was homozygous and identical to one of 
      the recipient's HLA haplotypes which indicated that the host would not resist 
      engraftment. On the basis of these findings, a diagnosis of chronic GVHD was 
      made, and increasing doses of immunosuppressants resulted in a resolution of 
      these symptoms. Our report is the first describing GVHD that developed in a 
      patient undergoing related-donor kidney transplantation.
FAU - Ohtsuka, Y
AU  - Ohtsuka Y
AD  - Division of Nephrology, Saga Medical School, Nabeshima, Japan.
FAU - Sakemi, T
AU  - Sakemi T
FAU - Ichigi, Y
AU  - Ichigi Y
FAU - Tanaka, T
AU  - Tanaka T
FAU - Nakamura, K
AU  - Nakamura K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Switzerland
TA  - Nephron
JT  - Nephron
JID - 0331777
SB  - IM
MH  - Adult
MH  - Chronic Disease
MH  - Fathers
MH  - Graft vs Host Disease/*etiology
MH  - Humans
MH  - Kidney Transplantation/*adverse effects
MH  - *Living Donors
MH  - Male
EDAT- 1998/03/13 03:03
MHDA- 2000/10/06 11:01
CRDT- 1998/03/13 03:03
PHST- 1998/03/13 03:03 [pubmed]
PHST- 2000/10/06 11:01 [medline]
PHST- 1998/03/13 03:03 [entrez]
AID - nef78215 [pii]
AID - 10.1159/000044914 [doi]
PST - ppublish
SO  - Nephron. 1998;78(2):215-7. doi: 10.1159/000044914.