PMID- 9505059
OWN - NLM
STAT- MEDLINE
DCOM- 19980409
LR  - 20181113
IS  - 1180-4882 (Print)
IS  - 1488-2434 (Electronic)
IS  - 1180-4882 (Linking)
VI  - 23
IP  - 1
DP  - 1998 Jan
TI  - Event-related potentials during a selective attention task with short 
      interstimulus intervals in patients with schizophrenia.
PG  - 45-50
AB  - OBJECTIVE: To study selective attention in schizophrenia by examining 
      event-related potentials during a dichotic listening task with short 
      interstimulus intervals (ISIs). DESIGN: Prospective study. PARTICIPANTS: Twelve 
      patients with schizophrenia in remission and 12 age-matched controls with no 
      history of psychiatric or neurological illness. INTERVENTIONS: Participants were 
      asked to push a button in response to target stimuli in either ear. OUTCOME 
      MEASURES: Reaction time, correct response rate and results of 
      electroencephalography recorded at 3 regions: mean segmental amplitudes between 0 
      and 200 ms and between 200 and 400 ms after stimuli and processing negativity 
      (Nd), measured by the negative area during these periods. RESULTS: Distinct 
      slow-positive potentials for unattended stimuli, which were elicited in a task 
      with long ISIs in a previous report, did not emerge in either group in this 
      study. Although the 2 groups did not differ significantly in terms of Nd area, in 
      the controls the mean segmental amplitude for attended standard stimuli was 
      significantly greater than that in the patients with schizophrenia. CONCLUSIONS: 
      Impairment of selective attention in patients with schizophrenia is related to a 
      lack of ability to focus attention on attended task-relevant stimuli during a 
      selective attention task with short ISI.
FAU - Iwanami, A
AU  - Iwanami A
AD  - Department of Psychiatry, Showa University School of Medicine, Tokyo, Japan. 
      iwanami@med.showa-u.ac.jp
FAU - Isono, H
AU  - Isono H
FAU - Okajima, Y
AU  - Okajima Y
FAU - Noda, Y
AU  - Noda Y
FAU - Kamijima, K
AU  - Kamijima K
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - J Psychiatry Neurosci
JT  - Journal of psychiatry & neuroscience : JPN
JID - 9107859
SB  - IM
MH  - Adult
MH  - Attention/*physiology
MH  - *Electroencephalography
MH  - Evoked Potentials
MH  - Female
MH  - Humans
MH  - Male
MH  - Prospective Studies
MH  - *Schizophrenic Psychology
PMC - PMC1188894
EDAT- 1998/03/20 00:00
MHDA- 1998/03/20 00:01
PMCR- 1998/01/01
CRDT- 1998/03/20 00:00
PHST- 1998/03/20 00:00 [pubmed]
PHST- 1998/03/20 00:01 [medline]
PHST- 1998/03/20 00:00 [entrez]
PHST- 1998/01/01 00:00 [pmc-release]
PST - ppublish
SO  - J Psychiatry Neurosci. 1998 Jan;23(1):45-50.