PMID- 9510000
OWN - NLM
STAT- MEDLINE
DCOM- 19980428
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 242
IP  - 1
DP  - 1998 Feb 6
TI  - Difference in water intake but not in renal sympathetic nerve activity in 
      response to central salt-loading or angiotensin II in awake Dahl salt-sensitive 
      and -resistant rats.
PG  - 41-4
AB  - Experiments were conducted to examine whether renal sympathetic nerve activity 
      (RSNA) and water intake in response to central salt-loading or angiotensin II (A 
      II) differ between freely-moving Dahl salt-sensitive (DS) and -resistant (DR) 
      rats maintained on a low-salt diet. Intracerebroventricular (i.c.v.) 
      administration of hypertonic saline (0.3 M, 1 microl/min, 20 min) or A II (100 
      ng/1 microl) evoked water intake, pressor response and suppression of RSNA in 
      both strains. The cumulative water intake in DS rats over a 60-min period after 
      i.c.v. infusion of hypertonic saline or A II was significantly attenuated 
      compared with that in DR rats. The RSNA response did not show a significant 
      difference between the strains. These results demonstrate that water intake, but 
      not RSNA response to acute central salt-loading or A II differ between awake DR 
      and DS rats.
FAU - Kato, K
AU  - Kato K
AD  - Department of Physiology, Miyazaki Medical College, Japan.
FAU - Saita, M
AU  - Saita M
FAU - Ishizuka, Y
AU  - Ishizuka Y
FAU - Nose, K
AU  - Nose K
FAU - Kunitake, T
AU  - Kunitake T
FAU - Hanamori, T
AU  - Hanamori T
FAU - Kannan, H
AU  - Kannan H
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Saline Solution, Hypertonic)
RN  - 0 (Sodium Chloride, Dietary)
RN  - 11128-99-7 (Angiotensin II)
SB  - IM
MH  - Angiotensin II/administration & dosage/*pharmacology
MH  - Animals
MH  - Blood Pressure/drug effects
MH  - Drinking/*drug effects
MH  - Drinking Behavior/drug effects
MH  - Heart Rate/drug effects
MH  - Injections, Intraventricular
MH  - Kidney/drug effects/*innervation
MH  - Male
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Saline Solution, Hypertonic/*administration & dosage
MH  - Sodium Chloride, Dietary/administration & dosage
MH  - Sympathetic Nervous System/*drug effects
EDAT- 1998/03/24 00:00
MHDA- 1998/03/24 00:01
CRDT- 1998/03/24 00:00
PHST- 1998/03/24 00:00 [pubmed]
PHST- 1998/03/24 00:01 [medline]
PHST- 1998/03/24 00:00 [entrez]
AID - S0304394098000056 [pii]
AID - 10.1016/s0304-3940(98)00005-6 [doi]
PST - ppublish
SO  - Neurosci Lett. 1998 Feb 6;242(1):41-4. doi: 10.1016/s0304-3940(98)00005-6.