PMID- 9526263 OWN - NLM STAT- MEDLINE DCOM- 19980602 LR - 20141120 IS - 1355-7610 (Print) IS - 1355-7610 (Linking) VI - 5 IP - 1 DP - 1998 Jan TI - Biocompatibility of dentine-bonding agents. 1. Factors associated with function. PG - 15-9 AB - The paper reviews the literature on the biocompatibility of dentine-bonding agents with respect to their ability to perform their defined function. Scanning electron microscope (SEM) pictures, prepared by the critical-point drying technique, are used to illustrate the various aspects of bonding to dentine such as the nature of dentine, the smear layer and the effects of primers, conditioners and etchants. From the review of the literature it can be concluded that the mechanisms of bonding to dentine are still not fully understood. The more recently introduced materials use mechanical means of adhesion where the dentine is altered by primers or conditioners to expose collagen fibres and a hybrid zone is created by the penetration of unfilled resins into this fibrous network. The irritant effects of a bonding agent on pulpal tissue may be caused by bacterial ingrowth due to initial poor bonding or a breakdown of the bond in addition to any inherent toxicity of the constituents of the bonding agent. FAU - Santini, A AU - Santini A LA - eng PT - Journal Article PT - Review PL - England TA - Prim Dent Care JT - Primary dental care : journal of the Faculty of General Dental Practitioners (UK) JID - 9617339 RN - 0 (Biocompatible Materials) RN - 0 (Dentin-Bonding Agents) EIN - Prim Dent Care 1998 Apr;5(2):72 MH - Bicuspid/drug effects/ultrastructure MH - Biocompatible Materials/*pharmacology MH - Dental Bonding MH - Dental Restoration, Permanent/methods MH - Dentin/*drug effects/ultrastructure MH - Dentin-Bonding Agents/*pharmacology MH - Humans MH - In Vitro Techniques MH - Microscopy, Electron, Scanning MH - Smear Layer RF - 21 EDAT- 1998/04/04 00:00 MHDA- 1998/04/04 00:01 CRDT- 1998/04/04 00:00 PHST- 1998/04/04 00:00 [pubmed] PHST- 1998/04/04 00:01 [medline] PHST- 1998/04/04 00:00 [entrez] PST - ppublish SO - Prim Dent Care. 1998 Jan;5(1):15-9.