PMID- 9547415 OWN - NLM STAT- MEDLINE DCOM- 19980515 LR - 20190512 IS - 0146-4760 (Print) IS - 0146-4760 (Linking) VI - 22 IP - 2 DP - 1998 Mar-Apr TI - Recent paramethoxyamphetamine deaths. PG - 169-72 AB - Paramethoxyamphetamine (PMA) is a methoxylated phenethylamine derivative that has been used illicitly in Australia since late 1994. It is purportedly sold under the guise of "ecstasy", which is the colloquial name for methylenedioxymethamphetamine (MDMA). Methods for extraction, identification, and quantitation are presented. Toxicology findings in six fatalities involving the drug are discussed. Femoral blood PMA levels ranged from 0.24 to 4.9 mg/L (mean, 2.3 mg/L). Liver PMA levels ranged from 1.4 to 21 mg/kg (mean, 8.9 mg/kg). Other amphetamines were found in five of the six cases. Blood PMA levels in three nonfatal cases are also presented. PMA appeared to be more toxic than MDMA, and blood levels greater than 0.5 mg/L seemed likely to be associated with toxic effects. FAU - Felgate, H E AU - Felgate HE AD - Forensic Science, Adelaide, South Australia, Australia. FAU - Felgate, P D AU - Felgate PD FAU - James, R A AU - James RA FAU - Sims, D N AU - Sims DN FAU - Vozzo, D C AU - Vozzo DC LA - eng PT - Case Reports PT - Journal Article PL - England TA - J Anal Toxicol JT - Journal of analytical toxicology JID - 7705085 RN - 0 (Central Nervous System Stimulants) RN - 0 (paramethoxymethamphetamine) RN - 44RAL3456C (Methamphetamine) SB - IM MH - Adult MH - Central Nervous System Stimulants/analysis/blood/*poisoning MH - Fatal Outcome MH - Female MH - Forensic Medicine MH - Humans MH - Liver/chemistry MH - Male MH - Methamphetamine/*analogs & derivatives/analysis/blood/poisoning MH - Poisoning/blood/*etiology/pathology EDAT- 1998/04/21 00:00 MHDA- 1998/04/21 00:01 CRDT- 1998/04/21 00:00 PHST- 1998/04/21 00:00 [pubmed] PHST- 1998/04/21 00:01 [medline] PHST- 1998/04/21 00:00 [entrez] AID - 10.1093/jat/22.2.169 [doi] PST - ppublish SO - J Anal Toxicol. 1998 Mar-Apr;22(2):169-72. doi: 10.1093/jat/22.2.169.