PMID- 9550363
OWN - NLM
STAT- MEDLINE
DCOM- 19980521
LR  - 20190816
IS  - 0009-9163 (Print)
IS  - 0009-9163 (Linking)
VI  - 53
IP  - 1
DP  - 1998 Jan
TI  - Association between asthma and an intragenic variant of CC16 on chromosome 11q13.
PG  - 54-6
AB  - The beta subunit of high affinity immunoglobulin E (IgE) receptor 
      (FcepsilonRIbeta) and the Clara cell derived inflammatory molecule, CC16 have 
      been cited as candidate genes for atopic asthma on chromosome 11q13. A genetic 
      association study was performed with an intragenic microsatellite repeat of CC16 
      gene on chromosome 11q12-13 in relation to atopic and non-atopic asthma. Whereas 
      variants of FcepsilonRIbeta at chromosome 11q13 show association with atopy and 
      asthma, no significant association was found between asthma and CC16 genotypes 
      irrespective of atopic status. These data support the candidacy of 
      FcepsilonRIbeta rather than CC16 for the atopic asthma locus on chromosome 11q.
FAU - Mao, X Q
AU  - Mao XQ
AD  - Department of Hygiene and Preventive Medicine, Osaka University School of 
      Medicine, Suita, Japan.
FAU - Shirakawa, T
AU  - Shirakawa T
FAU - Kawai, M
AU  - Kawai M
FAU - Enomoto, T
AU  - Enomoto T
FAU - Sasaki, S
AU  - Sasaki S
FAU - Dake, Y
AU  - Dake Y
FAU - Kitano, H
AU  - Kitano H
FAU - Hagihara, A
AU  - Hagihara A
FAU - Hopkin, J M
AU  - Hopkin JM
FAU - Morimoto, K
AU  - Morimoto K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Denmark
TA  - Clin Genet
JT  - Clinical genetics
JID - 0253664
RN  - 0 (Proteins)
RN  - 0 (SCGB1A1 protein, human)
RN  - 9060-09-7 (Uteroglobin)
SB  - IM
MH  - Adult
MH  - Alleles
MH  - Asthma/*genetics
MH  - Child
MH  - *Chromosomes, Human, Pair 16
MH  - Gene Frequency
MH  - *Genetic Variation
MH  - Humans
MH  - Proteins/*genetics
MH  - *Uteroglobin
EDAT- 1998/04/29 00:00
MHDA- 1998/04/29 00:01
CRDT- 1998/04/29 00:00
PHST- 1998/04/29 00:00 [pubmed]
PHST- 1998/04/29 00:01 [medline]
PHST- 1998/04/29 00:00 [entrez]
AID - 10.1034/j.1399-0004.1998.531530111.x [doi]
PST - ppublish
SO  - Clin Genet. 1998 Jan;53(1):54-6. doi: 10.1034/j.1399-0004.1998.531530111.x.