PMID- 9562214
OWN - NLM
STAT- MEDLINE
DCOM- 19980609
LR  - 20131121
IS  - 0172-4622 (Print)
IS  - 0172-4622 (Linking)
VI  - 19
IP  - 2
DP  - 1998 Feb
TI  - Effect of carbohydrate supplementation on plasma glutamine during prolonged 
      exercise and recovery.
PG  - 82-6
AB  - Muscle glycogen and glucose have been suggested to be carbon-chain precursors for 
      glutamine synthesis in skeletal muscle. Therefore, the aim of the present study 
      is to investigate whether carbohydrate supplementation affects plasma glutamine 
      and other amino acids during exercise and 7 h of recovery. Eight well-trained 
      subjects cycled at an alternating workload of 50 and 80% Wmax until exhaustion 
      (59 to 140 min). During the exercise bout the subjects received either water 
      (control) or a carbohydrate (CHO) drink (83 g CHO x l(-1), 2 ml x kg(-1) per kg 
      body weight every 15 min). Plasma glutamine concentration appeared not to be 
      affected by exercise, as a significant increase was only observed at some points 
      in time during the control test. During recovery, however, plasma glutamine 
      concentration decreased from 682+/-24 and 685+/-19 micromol x l(-1) at exhaustion 
      to 552+/-19 and 534+/-12 micromol x l(-1) after 2 h of recovery for the control 
      and CHO test, respectively. Plasma glutamine concentration returned to 
      pre-exercise values after 7 h of recovery. Alanine concentration increased during 
      exercise in both tests. During the recovery period the concentration of alanine 
      (48%), and total amino acids (23%) decreased below the pre-exercise level. The 
      plasma alanine and the total amino acid concentration was still suppressed after 
      7 h of recovery. In conclusion, carbohydrate supplementation had neither an 
      effect during exercise nor during recovery on the concentration of plasma 
      glutamine or other amino acids. Exercise, however, causes a substantial decrease 
      in the plasma amino acid concentration during recovery.
FAU - van Hall, G
AU  - van Hall G
AD  - Department of Human Biology University of Maastricht, The Netherlands.
FAU - Saris, W H
AU  - Saris WH
FAU - Wagenmakers, A J
AU  - Wagenmakers AJ
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Amino Acids)
RN  - 0 (Amino Acids, Branched-Chain)
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Lactates)
RN  - 059QF0KO0R (Water)
RN  - 0RH81L854J (Glutamine)
RN  - 7664-41-7 (Ammonia)
RN  - 9005-79-2 (Glycogen)
RN  - IY9XDZ35W2 (Glucose)
RN  - OF5P57N2ZX (Alanine)
SB  - IM
MH  - Adult
MH  - Alanine/blood
MH  - Amino Acids/blood
MH  - Amino Acids, Branched-Chain/blood
MH  - Ammonia/blood
MH  - Analysis of Variance
MH  - Bicycling/*physiology
MH  - Blood Glucose/analysis
MH  - Dietary Carbohydrates/*administration & dosage/metabolism
MH  - *Dietary Supplements
MH  - Exercise Test
MH  - Exercise Tolerance
MH  - Glucose/*administration & dosage/metabolism
MH  - Glutamine/biosynthesis/*blood
MH  - Glycogen/metabolism
MH  - Humans
MH  - Lactates/blood
MH  - Male
MH  - Muscle, Skeletal/metabolism
MH  - Physical Exertion/physiology
MH  - Rest
MH  - Time Factors
MH  - Water/administration & dosage
EDAT- 1998/04/30 00:00
MHDA- 1998/04/30 00:01
CRDT- 1998/04/30 00:00
PHST- 1998/04/30 00:00 [pubmed]
PHST- 1998/04/30 00:01 [medline]
PHST- 1998/04/30 00:00 [entrez]
AID - 10.1055/s-2007-971886 [doi]
PST - ppublish
SO  - Int J Sports Med. 1998 Feb;19(2):82-6. doi: 10.1055/s-2007-971886.