PMID- 9562892 OWN - NLM STAT- MEDLINE DCOM- 19980430 LR - 20191024 IS - 0920-8569 (Print) IS - 0920-8569 (Linking) VI - 16 IP - 1 DP - 1998 TI - The origin and evolution of human T-cell lymphotropic virus types I and II. PG - 69-84 AB - Studies on human T-cell lymphotropic virus types I (HTLV-I) and II (HTLV-II) are briefly reviewed from the viewpoint of molecular evolution, with special reference to the evolutionary rate and evolutionary relationships among these viruses. In particular, it appears that, in contrast to the low level of variability of HTLV-I among different isolates, individual isolates form quasispecies structures. Elucidating the mechanisms connecting these two phenomena will be one of the future problems in the study of the molecular evolution of HTLV-I and HTLV-II. FAU - Suzuki, Y AU - Suzuki Y AD - Center for Information Biology, National Institute of Genetics, Mishima, Japan. FAU - Gojobori, T AU - Gojobori T LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - United States TA - Virus Genes JT - Virus genes JID - 8803967 SB - IM MH - *Evolution, Molecular MH - HTLV-I Infections/transmission MH - HTLV-II Infections/transmission MH - Human T-lymphotropic virus 1/*genetics/pathogenicity MH - Human T-lymphotropic virus 2/*genetics/pathogenicity MH - Humans MH - Topography, Medical RF - 298 EDAT- 1998/05/01 00:00 MHDA- 1998/05/01 00:01 CRDT- 1998/05/01 00:00 PHST- 1998/05/01 00:00 [pubmed] PHST- 1998/05/01 00:01 [medline] PHST- 1998/05/01 00:00 [entrez] AID - 10.1023/a:1007953826869 [doi] PST - ppublish SO - Virus Genes. 1998;16(1):69-84. doi: 10.1023/a:1007953826869.