PMID- 9562928
OWN - NLM
STAT- MEDLINE
DCOM- 19980529
LR  - 20061115
IS  - 0147-958X (Print)
IS  - 0147-958X (Linking)
VI  - 21
IP  - 2
DP  - 1998 Apr
TI  - Exercise capacity and energy expenditure of morbidly obese and previously obese 
      subjects.
PG  - 79-87
AB  - OBJECTIVE: To determine whether morbidly obese and previously obese women fail to 
      lose weight after gastric bypass surgery because of reduced energy expenditure, 
      and whether a large, surgically induced, rapid weight loss improves exercise 
      capacity on a treadmill. DESIGN: Cross-sectional study. PARTICIPANTS: Four groups 
      of 5 subjects: 1) patients still obese 12 months after surgery (failure); 2) 
      patients who achieved normal weight after surgery (success); 3) obese patients 
      who had not yet undergone surgery (preoperative); and 4) nonobese (control) 
      subjects. Four subjects in the preoperative group were studied again at 6 months 
      postsurgery. MAIN OUTCOME MEASURES: Total daily energy expenditure (TDEE), and 
      exercise capacity and peak oxygen consumption (VO2) during treadmill exercise. 
      RESULTS: TDEE or energy expenditure (EE) above basal metabolic rate (when 
      normalized for body size) was similar for all groups, but the absolute energy 
      consumption was higher in the preoperative and failure groups. Treadmill 
      endurance time was greater in the success than the failure and preoperative 
      groups, and the endurance times of these 3 groups were less than those of the 
      nonobese subjects. Peak VO2 body weight was similar in the success, failure and 
      preoperative groups, which meant that the peak VO2 was lower in the success group 
      than in the preoperative and failure groups. Six months after surgery, peak VO2 
      had not decreased in the preoperative group. CONCLUSION: Failure to lose weight 
      after isolated gastric bypass surgery was not because of a lower level of 
      activity. Aerobic capacity was impaired 1 year, but not 6 months, after a large 
      weight loss. Exercise training may be appropriate to maintain absolute peak 
      oxygen consumption.
FAU - Notarius, C F
AU  - Notarius CF
AD  - Division of Critical Care, McGill University, Montreal, Que. 
      smagder@rvhmed.lan.mcgill.ca
FAU - Rhode, B
AU  - Rhode B
FAU - MacLean, L D
AU  - MacLean LD
FAU - Magder, S
AU  - Magder S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - Clin Invest Med
JT  - Clinical and investigative medicine. Medecine clinique et experimentale
JID - 7804071
SB  - IM
MH  - Adult
MH  - Cross-Sectional Studies
MH  - *Energy Metabolism
MH  - Exercise/*physiology
MH  - Female
MH  - *Gastric Bypass
MH  - Heart Rate
MH  - Humans
MH  - Longitudinal Studies
MH  - Obesity/*metabolism/surgery
MH  - Obesity, Morbid/*metabolism/surgery
MH  - Oxygen Consumption
MH  - Treatment Outcome
MH  - Weight Loss
EDAT- 1998/05/01 00:00
MHDA- 1998/05/01 00:01
CRDT- 1998/05/01 00:00
PHST- 1998/05/01 00:00 [pubmed]
PHST- 1998/05/01 00:01 [medline]
PHST- 1998/05/01 00:00 [entrez]
PST - ppublish
SO  - Clin Invest Med. 1998 Apr;21(2):79-87.