PMID- 9569892 OWN - NLM STAT- MEDLINE DCOM- 19980507 LR - 20191210 IS - 0022-3018 (Print) IS - 0022-3018 (Linking) VI - 186 IP - 4 DP - 1998 Apr TI - Defensive functioning predicts improvement in major depressive episodes. PG - 238-43 AB - We investigated the predictive effect of psychological defenses on the course of major depression in a subsample of psychiatric patients from a larger study. We tested the hypothesis that a group of eight defenses, associated with depression in previous research, would predict, outcome of major depression. After an intake interview, 37 patients were rated on all DSM-III-R Axes, the SCL-90-R, and 28 defenses, using the Defense Mechanism Rating Scales. At 6-month follow-up interview, SCL-90-R and Global Assessment and Functioning (GAF) were redetermined on 34 (92%), 16 of whom had major depression at intake. Overall Defensive Functioning (ODF) significantly predicted GAF at 6-month follow-up over and above initial level of global functioning and presence of a personality disorder. The group of eight defenses were identified more often (p = .068) in depressed patients who improved less than predicted by their initial functional status. The high adaptive level defense, self-observation, was identified more often in those who improved more than predicted by their initial status. Our findings support the theory of a hierarchy of defenses, and the mediating effects of specific low and high adaptive level defenses on the course of a major depressive episode. Further research should examine passive aggression, acting out, help-rejecting complaining, splitting of self-images, splitting of others' images, projective identification, projection, and devaluation in relationship to the onset, course, and treatment response of depressive disorders. FAU - Hoglend, P AU - Hoglend P AD - Department of Psychiatry, University of Oslo, Norway. FAU - Perry, J C AU - Perry JC LA - eng PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't PL - United States TA - J Nerv Ment Dis JT - The Journal of nervous and mental disease JID - 0375402 SB - IM MH - Adult MH - Comorbidity MH - *Defense Mechanisms MH - Depressive Disorder/*diagnosis/epidemiology/psychology MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Outcome Assessment, Health Care MH - Personality Disorders/diagnosis/epidemiology MH - Probability MH - Prognosis MH - Psychiatric Status Rating Scales/statistics & numerical data MH - Regression Analysis MH - Reproducibility of Results MH - Severity of Illness Index EDAT- 1998/05/07 00:00 MHDA- 1998/05/07 00:01 CRDT- 1998/05/07 00:00 PHST- 1998/05/07 00:00 [pubmed] PHST- 1998/05/07 00:01 [medline] PHST- 1998/05/07 00:00 [entrez] AID - 10.1097/00005053-199804000-00006 [doi] PST - ppublish SO - J Nerv Ment Dis. 1998 Apr;186(4):238-43. doi: 10.1097/00005053-199804000-00006.