PMID- 9577650
OWN - NLM
STAT- MEDLINE
DCOM- 19980701
LR  - 20061115
IS  - 0009-918X (Print)
IS  - 0009-918X (Linking)
VI  - 37
IP  - 12
DP  - 1997 Dec
TI  - [A report from neurological practice].
PG  - 1079-87
AB  - It was one of the great pleasures to have fulfilled my long-held dream in 1986, 
      newly opened the Kitasato University East Hospital (KUEH). In 1965, I served at 
      chronic ward of Baltimore City Hospitals as a resident of neurology, where most 
      of the patients were relaxed and enjoyed their hospital life. Since then, my 
      dream had been growing that chronic ward for neurological diseases was necessary 
      in Japan, good for chronic cares as well as clinical research. KUEH include 89 
      beds for neurological diseases, uniquely enough, of which 15 beds specially 
      prepared for the patients with respiratory distress suffering from intractable 
      neurological diseases. KUEH gave us a lot of medical informations, developed to 
      clinical research. Some of them will be introduced briefly as follows; firstly, 
      in three patients with Guillain-Barre syndrome (GBS) we found high titers of 
      serum IgM and IgG antibodies associated with acute cytomegalovirus (CMV) 
      infections. They also had high titers of IgM and IgG anti-GM2 antibodies. The 
      titers of anti-GM2 antibodies decreased on absorption with CMV-infected cells. 
      These new findings suggested that anti-GM2 antibodies are associated with acute 
      CMV infections in GBS patients. Secondly, we have patients with autosomal 
      dominant familial Parkinsonism in Sagamihara, Kanagawa. Their clinical features 
      are not essentially different from solitary Parkinson disease, and they respond 
      well to levodopa treatment. Three autopsied cases, however, revealed 
      neuropathological findings much different from those of classical Parkinson 
      disease, such as rather mild to moderate loss of melanin-containing cells, 
      well-maintained locus ceruleus neurons in number and no Lewy bodies detected at 
      all. There are no reports in literatures of familial Parkinsonism from clinical 
      and neuropathological points of view. Thirty-eight years have passed since 
      establishment of the Japan Neurological Society, meanwhile the expertise 
      neurologists come out. Neurology is, however, still minor in medical practice. 
      This is my opinion that neurologist should take leadership in clinical medicine 
      as well as in academic fields. We need tell people our work, how our neurologic 
      expertise can help them treat various disorders such as stroke, pain, sleep, and 
      headache, epilepsy as well as physical and mental rehabilitation for the 
      establishment of our identity.
FAU - Kowa, H
AU  - Kowa H
AD  - Department of Neurology, Kitasato University East Hospital.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Shinkeigaku
JT  - Rinsho shinkeigaku = Clinical neurology
JID - 0417466
SB  - IM
MH  - Humans
MH  - Japan
MH  - Neurology/*trends
EDAT- 1998/05/13 00:00
MHDA- 1998/05/13 00:01
CRDT- 1998/05/13 00:00
PHST- 1998/05/13 00:00 [pubmed]
PHST- 1998/05/13 00:01 [medline]
PHST- 1998/05/13 00:00 [entrez]
PST - ppublish
SO  - Rinsho Shinkeigaku. 1997 Dec;37(12):1079-87.