PMID- 9578423
OWN - NLM
STAT- MEDLINE
DCOM- 19980609
LR  - 20061115
IS  - 0960-8931 (Print)
IS  - 0960-8931 (Linking)
VI  - 7 Suppl 2
DP  - 1997 Aug
TI  - New tumour-restricted melanoma antigens as defined by cytotoxic T-cell responses.
PG  - S95-8
AB  - Several tumour antigens have been molecularly defined during the last few years 
      and three main groups of melanoma-associated antigens have been identified 
      according to their pattern of expression. Despite their wide expression in the 
      Caucasian population, human leukocyte antigen (HLA) class I-presenting molecules, 
      alternate to HLA-A2.1, have received little attention. To further explore the 
      complexity of HLA class I-presented melanoma epitopes, we looked for the 
      existence of other antigens recognized by T cells in HLA-A3.1 and HLA-A2.1 
      restriction. The pattern of recognition identified by HLA-A3.1 or 
      HLA-A2.1-restricted T-cell lines and clones indicated the existence of a novel 
      category of antigens represented by proteins expressed by melanomase but not by 
      melanocytes.
FAU - Parmiani, G
AU  - Parmiani G
AD  - Division of Experimental Oncology D, Istituto Nazionale Tumori, Milan, Italy.
FAU - Anichini, A
AU  - Anichini A
FAU - Castelli, C
AU  - Castelli C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Melanoma Res
JT  - Melanoma research
JID - 9109623
RN  - 0 (Antigens, Neoplasm)
RN  - 0 (HLA-A2 Antigen)
RN  - 0 (HLA-A3 Antigen)
SB  - IM
MH  - Antigens, Neoplasm/*immunology
MH  - HLA-A2 Antigen/*immunology
MH  - HLA-A3 Antigen/*immunology
MH  - Humans
MH  - Lymphocyte Activation/*immunology
MH  - Melanocytes/immunology
MH  - Melanoma/*immunology
MH  - T-Lymphocytes, Cytotoxic/*immunology
RF  - 11
EDAT- 1997/08/01 00:00
MHDA- 1998/05/13 00:01
CRDT- 1997/08/01 00:00
PHST- 1997/08/01 00:00 [pubmed]
PHST- 1998/05/13 00:01 [medline]
PHST- 1997/08/01 00:00 [entrez]
PST - ppublish
SO  - Melanoma Res. 1997 Aug;7 Suppl 2:S95-8.