PMID- 9580418 OWN - NLM STAT- MEDLINE DCOM- 19980610 LR - 20071115 IS - 0390-6078 (Print) IS - 0390-6078 (Linking) VI - 83 IP - 3 DP - 1998 Mar TI - Unexpected late graft failure 9 months after HLA-identical bone marrow transplant (BMT) for chronic myeloid leukemia (CML): treatment with a second BMT. PG - 285-7 AB - We describe a patient with CML in 1st chronic phase (CP) who experienced a graft failure 9 months after an HLA genotypically identical sibling BMT. Drug toxicity, viral infections, chronic graft-versus-host-disease (GVHD) or leukemic relapse were excluded. Chimerism study showed 85% of donor marrow cells. She underwent a second BMT, reengrafted but died of grade IV acute GVHD. FAU - Gil-Fernandez, J J AU - Gil-Fernandez JJ FAU - Arranz, R AU - Arranz R FAU - Camara, R AU - Camara R FAU - Alegre, A AU - Alegre A FAU - Figuera, A AU - Figuera A FAU - Fernandez-Ranada, J M AU - Fernandez-Ranada JM LA - eng PT - Case Reports PT - Letter PL - Italy TA - Haematologica JT - Haematologica JID - 0417435 RN - 0 (HLA Antigens) SB - IM MH - Adult MH - Bone Marrow Transplantation/adverse effects/*immunology MH - Female MH - Graft Rejection/*etiology MH - Graft vs Host Disease/etiology MH - HLA Antigens/analysis MH - Humans MH - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*complications/*therapy MH - Reoperation MH - Time Factors EDAT- 1998/05/15 00:00 MHDA- 1998/05/15 00:01 CRDT- 1998/05/15 00:00 PHST- 1998/05/15 00:00 [pubmed] PHST- 1998/05/15 00:01 [medline] PHST- 1998/05/15 00:00 [entrez] PST - ppublish SO - Haematologica. 1998 Mar;83(3):285-7.