PMID- 9596155 OWN - NLM STAT- MEDLINE DCOM- 19980715 LR - 20190721 IS - 0363-9762 (Print) IS - 0363-9762 (Linking) VI - 23 IP - 5 DP - 1998 May TI - Usefulness of scintigraphy with Tc-99m phytate for the diagnosis of alcoholic foamy degeneration. PG - 302-4 AB - PURPOSE: Alcoholic foamy degeneration (AFD) is a liver disease causing temporary hepatocyte dysfunction. The prognosis is usually good, but liver biopsy is needed for diagnosis. We report the usefulness of liver-spleen scintigraphy with the radiocolloid Tc-99m phytate for the diagnosis of AFD. PATIENTS AND METHODS: We used liver scintigraphy with Tc-99m phytate to study three patients with AFD diagnosed on the basis of findings from a liver biopsy. RESULTS: Liver-spleen scintigraphy showed hepatomegaly and splenomegaly, and bone marrow was visible, but radioisotope uptake by the liver was uniform. CONCLUSIONS: This pattern of scintigraphic findings is different from that reported for patients with alcoholic fatty livers or severe alcoholic hepatitis, and seems to be specific for AFD. FAU - Shiomi, S AU - Shiomi S AD - Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan. FAU - Sasaki, N AU - Sasaki N FAU - Yokogawa, T AU - Yokogawa T FAU - Kawada, N AU - Kawada N FAU - Sakaguchi, H AU - Sakaguchi H FAU - Nakajima, S AU - Nakajima S FAU - Kuroki, T AU - Kuroki T FAU - Kawabe, J AU - Kawabe J FAU - Ochi, H AU - Ochi H LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Clin Nucl Med JT - Clinical nuclear medicine JID - 7611109 RN - 0 (Organotechnetium Compounds) RN - 0 (Radiopharmaceuticals) RN - 0 (technetium phytate) RN - 7IGF0S7R8I (Phytic Acid) SB - IM MH - Adult MH - Biopsy MH - Diagnosis, Differential MH - Fatty Liver, Alcoholic/diagnostic imaging MH - Female MH - Hepatitis, Alcoholic/diagnostic imaging MH - Hepatomegaly/diagnostic imaging MH - Humans MH - Liver/diagnostic imaging/pathology MH - Liver Diseases, Alcoholic/*diagnostic imaging/pathology MH - Male MH - *Organotechnetium Compounds MH - *Phytic Acid MH - Prognosis MH - Radionuclide Imaging MH - *Radiopharmaceuticals MH - Spleen/diagnostic imaging MH - Splenomegaly/diagnostic imaging EDAT- 1998/05/22 00:00 MHDA- 1998/05/22 00:01 CRDT- 1998/05/22 00:00 PHST- 1998/05/22 00:00 [pubmed] PHST- 1998/05/22 00:01 [medline] PHST- 1998/05/22 00:00 [entrez] AID - 10.1097/00003072-199805000-00007 [doi] PST - ppublish SO - Clin Nucl Med. 1998 May;23(5):302-4. doi: 10.1097/00003072-199805000-00007.