PMID- 9603556
OWN - NLM
STAT- MEDLINE
DCOM- 19980709
LR  - 20220321
IS  - 1055-6656 (Print)
IS  - 1055-6656 (Linking)
VI  - 35
IP  - 3
DP  - 1998 May
TI  - Short-term cost-effectiveness analysis of presurgical orthopedic treatment in 
      children with complete unilateral cleft lip and palate.
PG  - 222-6
AB  - OBJECTIVE: The aim of this article was to investigate cost-effectiveness in cleft 
      palate treatment using cost-effectiveness of presurgical orthopedic treatment 
      (PSOT) as an example. DESIGN: A three-center randomized clinical trial compared 
      PSOT with non-PSOT for children with unilateral cleft lip and palate (UCLP, 
      n=52). PATIENTS: The inclusion criteria for the trial were: complete UCLP, no 
      other malformations, born at term, both parents Caucasian, trial entrance 
      preferably within 2 weeks after birth, and informed consent by the parents. 
      INTERVENTIONS: PSOT was performed by means of a passive plate according to Hotz 
      and Gnoinski. MAIN OUTCOME MEASURE: The short-term cost-effectiveness of PSOT was 
      based on the time taken for the surgical lip closure procedure. Medical and 
      nonmedical costs until surgical lip closure at 18 weeks of age were analyzed. 
      RESULTS: The durations of the surgical lip closure procedures did not differ 
      significantly (57.2 minutes for PSOT and 56.4 minutes for non-PSOT). The mean 
      medical cost for PSOT treatment was US$852. The non-PSOT treatment group had a 
      significantly different mean medical cost (US$304). Mean travel costs and 
      indirect nonmedical costs were US$128 and US$231 for PSOT and US$79 and US$130 
      for non-PSOT, respectively. CONCLUSIONS: The combination of a clinical trial and 
      an economic evaluation makes it possible to relate effects to costs involved in 
      treatment alternatives. Longer-term costs and effects will be incorporated into 
      an extended cost-effectiveness analysis to determine the cost-effectiveness of 
      PSOT.
FAU - Severens, J L
AU  - Severens JL
AD  - Department of Medical Informatics, Epidemiology and Statistics, University of 
      Nijmegen, The Netherlands. h.severens@mie.kun.nl
FAU - Prahl, C
AU  - Prahl C
FAU - Kuijpers-Jagtman, A M
AU  - Kuijpers-Jagtman AM
FAU - Prahl-Andersen, B
AU  - Prahl-Andersen B
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cleft Palate Craniofac J
JT  - The Cleft palate-craniofacial journal : official publication of the American 
      Cleft Palate-Craniofacial Association
JID - 9102566
SB  - IM
MH  - Analysis of Variance
MH  - Cleft Lip/surgery/*therapy
MH  - Cleft Palate/surgery/*therapy
MH  - Cost-Benefit Analysis
MH  - Follow-Up Studies
MH  - Health Care Costs
MH  - Hospital Costs
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Orthodontics, Corrective/*economics
MH  - Palatal Obturators/*economics
MH  - Sensitivity and Specificity
MH  - Time Factors
MH  - Travel/economics
EDAT- 1998/05/29 00:00
MHDA- 1998/05/29 00:01
CRDT- 1998/05/29 00:00
PHST- 1998/05/29 00:00 [pubmed]
PHST- 1998/05/29 00:01 [medline]
PHST- 1998/05/29 00:00 [entrez]
AID - 10.1597/1545-1569_1998_035_0222_stceao_2.3.co_2 [doi]
PST - ppublish
SO  - Cleft Palate Craniofac J. 1998 May;35(3):222-6. doi: 
      10.1597/1545-1569_1998_035_0222_stceao_2.3.co_2.