PMID- 9618874
OWN - NLM
STAT- MEDLINE
DCOM- 19980814
LR  - 20190702
IS  - 0042-4900 (Print)
IS  - 0042-4900 (Linking)
VI  - 142
IP  - 19
DP  - 1998 May 9
TI  - Effect on viraemia of an American and a European serotype PRRSV vaccine after 
      challenge with European wild-type strains of the virus.
PG  - 510-2
AB  - Three groups of 10 pigs were vaccinated with an American serotype porcine 
      reproductive and respiratory syndrome virus (PRRSV) vaccine and three groups of 
      10 pigs were vaccinated with a European serotype PRRSV vaccine. A control group 
      of 12 pigs was left unvaccinated. Four weeks after vaccination the PRRSV-specific 
      antibody titres were determined and each group was challenged with either a 
      Spanish, German or Dutch PRRSV wild-type strain. The serological responses four 
      weeks after vaccination confirmed that the two vaccines were of different 
      serotypes. Vaccination with the American serotype vaccine hardly reduced the 
      level of viraemia after challenge with the European PRRSV wild-type strains, and 
      only after challenge with the Spanish PRRSV strain was a moderate, statistically 
      significant reduction in viraemia observed. In contrast, after vaccination with 
      the European serotype vaccine, viraemia was completely suppressed after challenge 
      with the German PRRSV isolate and almost completely suppressed after challenge 
      with the Spanish and Dutch PRRSV isolates.
FAU - van Woensel, P A
AU  - van Woensel PA
AD  - Intervet International BV, Boxmeer, The Netherlands.
FAU - Liefkens, K
AU  - Liefkens K
FAU - Demaret, S
AU  - Demaret S
LA  - eng
PT  - Journal Article
PL  - England
TA  - Vet Rec
JT  - The Veterinary record
JID - 0031164
RN  - 0 (Viral Vaccines)
SB  - IM
MH  - Animals
MH  - Europe
MH  - Porcine Reproductive and Respiratory Syndrome/*prevention & control/virology
MH  - Porcine respiratory and reproductive syndrome virus/*immunology
MH  - Swine
MH  - United States
MH  - Vaccination/veterinary
MH  - Viral Vaccines/*therapeutic use
MH  - Viremia/prevention & control/*veterinary
EDAT- 1998/06/10 00:00
MHDA- 1998/06/10 00:01
CRDT- 1998/06/10 00:00
PHST- 1998/06/10 00:00 [pubmed]
PHST- 1998/06/10 00:01 [medline]
PHST- 1998/06/10 00:00 [entrez]
AID - 10.1136/vr.142.19.510 [doi]
PST - ppublish
SO  - Vet Rec. 1998 May 9;142(19):510-2. doi: 10.1136/vr.142.19.510.