PMID- 9620431 OWN - NLM STAT- MEDLINE DCOM- 19980728 LR - 20200724 IS - 0095-1137 (Print) IS - 1098-660X (Electronic) IS - 0095-1137 (Linking) VI - 36 IP - 6 DP - 1998 Jun TI - Defective human T-cell lymphotropic virus type I (HTLV-I) provirus in 10 Chilean seronegative patients with tropical spastic paraparesis or HTLV-I-associated myelopathy. PG - 1811-3 AB - We studied the presence of tax and ltr genes from human T-cell lymphotropic virus type I (HTLV-I) provirus in the peripheral blood mononuclear cells from 15 seronegative patients with tropical spastic paraparesis or HTLV-I-associated myelopathy by PCR. Only a region of the tax gene from 10 patients was amplified. The nucleotide homologies of six Chilean isolates to the ATK-1 clone ranged between 98.7 and 99.4%. FAU - Ramirez, E AU - Ramirez E AD - Department of Health Laboratories, Public Health Institute of Chile, Santiago. eramirez@ispch.cl FAU - Cartier, L AU - Cartier L FAU - Rios, M AU - Rios M FAU - Fernandez, J AU - Fernandez J LA - eng PT - Journal Article PL - United States TA - J Clin Microbiol JT - Journal of clinical microbiology JID - 7505564 RN - 0 (HTLV-I Antibodies) SB - IM MH - Adult MH - Aged MH - Base Sequence MH - Blotting, Western MH - Chile MH - Defective Viruses/genetics/*isolation & purification MH - Female MH - Fluorescent Antibody Technique, Indirect MH - Genes, pX MH - HTLV-I Antibodies/blood MH - HTLV-I Infections/immunology/*virology MH - Human T-lymphotropic virus 1/genetics/*isolation & purification MH - Humans MH - Male MH - Middle Aged MH - Molecular Sequence Data MH - Paraparesis, Tropical Spastic/immunology/*virology MH - Polymerase Chain Reaction MH - Proviruses/genetics/*isolation & purification PMC - PMC104931 EDAT- 1998/06/10 00:00 MHDA- 1998/06/10 00:01 PMCR- 1998/06/01 CRDT- 1998/06/10 00:00 PHST- 1998/06/10 00:00 [pubmed] PHST- 1998/06/10 00:01 [medline] PHST- 1998/06/10 00:00 [entrez] PHST- 1998/06/01 00:00 [pmc-release] AID - 0922 [pii] AID - 10.1128/JCM.36.6.1811-1813.1998 [doi] PST - ppublish SO - J Clin Microbiol. 1998 Jun;36(6):1811-3. doi: 10.1128/JCM.36.6.1811-1813.1998.