PMID- 9637610
OWN - NLM
STAT- MEDLINE
DCOM- 19980625
LR  - 20190813
IS  - 0013-9580 (Print)
IS  - 0013-9580 (Linking)
VI  - 39
IP  - 6
DP  - 1998 Jun
TI  - Fixation-off and eyes closed catamenial generalized nonconvulsive status 
      epilepticus with eyelid myoclonic jerks.
PG  - 664-8
AB  - PURPOSE: Eyelid myoclonic jerks have been described in fixation-off-sensitive 
      (FOS) epilepsy, but their relationship to nonconvulsive status epilepticus (NCSE) 
      or to catamenial exacerbations is little reported. METHODS: We describe a woman 
      of normal intelligence with catamenial periods of prolonged NCSE who exhibited 
      various intra- and interseizure thresholds of polyspike suppression when her eyes 
      were open, with particular visual inputs and with antiepileptic drug (AED) 
      treatment. RESULTS: In one episode, on the first day of the woman's menstrual 
      period, bursts of bilateral synchronous polyspike activity were briefly 
      suppressed with visual fixation but were more lastingly suppressed after 
      administration of lorazepam (LZP). During another period of NCSE, the SE was 
      completely suppressed by visual fixation on objects and patterned checkerboard 
      screens and by ocular convergence, was incompletely suppressed when her eyes were 
      open in a dark room and when her eyes were open without visual fixation, but was 
      not suppressed by mental activation alone. CONCLUSIONS: FOS polyspike bursts with 
      eyelid myoclonic jerks may exhibit catamenial exacerbations, varying from 
      completely suppressible with visual fixation to nonsuppressible during NCSE. 
      These findings suggest an interplay between humoral factors, AEDs, and seizure 
      threshold in this condition.
FAU - Ming, X
AU  - Ming X
AD  - Division of Pediatric Neurology, University of Medicine and Dentistry of New 
      Jersey, New Jersey Medical School, Newark, USA.
FAU - Kaplan, P W
AU  - Kaplan PW
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
SB  - IM
MH  - Adult
MH  - Electroencephalography/statistics & numerical data
MH  - Epilepsies, Myoclonic/*diagnosis/physiopathology
MH  - Epilepsy, Absence/diagnosis/physiopathology
MH  - Eyelids/*physiopathology
MH  - Female
MH  - Fixation, Ocular/*physiology
MH  - Humans
MH  - Menstruation/*physiology
MH  - Status Epilepticus/*diagnosis/physiopathology
MH  - Visual Perception/physiology
EDAT- 1998/06/24 00:00
MHDA- 1998/06/24 00:01
CRDT- 1998/06/24 00:00
PHST- 1998/06/24 00:00 [pubmed]
PHST- 1998/06/24 00:01 [medline]
PHST- 1998/06/24 00:00 [entrez]
AID - 10.1111/j.1528-1157.1998.tb01436.x [doi]
PST - ppublish
SO  - Epilepsia. 1998 Jun;39(6):664-8. doi: 10.1111/j.1528-1157.1998.tb01436.x.