PMID- 9639769
OWN - NLM
STAT- MEDLINE
DCOM- 19980722
LR  - 20061115
IS  - 0529-567X (Print)
IS  - 0529-567X (Linking)
VI  - 32
IP  - 11
DP  - 1997 Nov
TI  - [The changes of T lymphocyte subsets and serum interleukin-2 receptor in 
      peripheral blood of the pregnant women complicated by systemic lupus 
      erythematosus].
PG  - 671-3
AB  - OBJECTIVE: To determine the changes of T lymphocyte subsets, natural killer (NK) 
      cell and serum interleukin-2 receptor (SIL-2R) in peripheral blood of the 
      pregnant women with systemic lupus erythematosus (SLE). METHODS: T lymphocyte 
      subsets NK cell, and SIL-2R in peripheral blood were detected by flow cytometry 
      (FCM) and enzyme-labeled immunosorbent assay (ELISA) in 14 cases of pregnant 
      women complicated by SLE (SLE+NP), 18 cases of stationary phase SLE (SLE), 20 
      cases of normal non-pregnant women (NNP) and 20 cases of normal pregnant women 
      (NP). RESULTS: The percentages of CD4+ cell were decreased significantly in 
      SLE+NP group as compared with the other three groups (P < 0.01); and the ratio of 
      CD4+/CD8+ was decreased significantly in SLE+NP group, as compared that in SLE 
      group and in NNP group (P < 0.01). There were no difference in the number of NK 
      cells among the four groups. The SIL-2R values were found to be increased 
      significantly in the SLE+NP group, as compared with that of other three groups (P 
      < 0.01). CONCLUSION: The observation on the changes of peripheral T lymphocyte 
      subsets and SIL-2R may be helpful for monitoring progress of SLE during 
      pregnancy.
FAU - Su, Y
AU  - Su Y
AD  - Renji Hospital, Shanghai Second Medical University.
FAU - Hong, S
AU  - Hong S
FAU - Zhao, A
AU  - Zhao A
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Fu Chan Ke Za Zhi
JT  - Zhonghua fu chan ke za zhi
JID - 16210370R
RN  - 0 (Receptors, Interleukin-2)
SB  - IM
MH  - Adult
MH  - CD4-CD8 Ratio
MH  - Female
MH  - Humans
MH  - Killer Cells, Natural/immunology
MH  - Lupus Erythematosus, Systemic/*immunology
MH  - Pregnancy
MH  - Pregnancy Complications/*immunology
MH  - Receptors, Interleukin-2/*metabolism
MH  - T-Lymphocyte Subsets/*immunology
EDAT- 1998/06/26 00:00
MHDA- 1998/06/26 00:01
CRDT- 1998/06/26 00:00
PHST- 1998/06/26 00:00 [pubmed]
PHST- 1998/06/26 00:01 [medline]
PHST- 1998/06/26 00:00 [entrez]
PST - ppublish
SO  - Zhonghua Fu Chan Ke Za Zhi. 1997 Nov;32(11):671-3.