PMID- 9645208
OWN - NLM
STAT- MEDLINE
DCOM- 19980714
LR  - 20190815
IS  - 0304-8608 (Print)
IS  - 0304-8608 (Linking)
VI  - 143
IP  - 5
DP  - 1998
TI  - HTLV-1 in mouthwash cells from a TSP/HAM patient and asymptomatic carriers.
PG  - 1029-34
AB  - Using in situ hybridization, the presence of T-cell lymphotrophic virus type I 
      (HTLV-I) was shown in blood lymphocytes of one tropical spastic paraparesis 
      (TSP/HAM) patient and in two asymptomatic carriers. HTLV-I was also detected in 
      epithelial cells derived from mouthwash of the TSP/HAM patient. Mouthwash of one 
      of the carriers showed an infected lymphocyte while mouthwash of the other 
      carrier was negative. The infected epithelial cells stained both in the nucleus 
      and in the cytoplasm, which indicated the presence of the virus in both 
      subcellular compartments. Our observations suggest that saliva cells, lymphocytes 
      and epithelial cells, may potentially participate in oral transmission of HTLV-I.
FAU - Offen, D
AU  - Offen D
AD  - Department of Neurology, Rabin Medical Center, Petah Tikva, Israel.
FAU - Achiron, A
AU  - Achiron A
FAU - Wasserman, L
AU  - Wasserman L
FAU - Miller, M
AU  - Miller M
FAU - Shaklai, M
AU  - Shaklai M
FAU - Dabby, R
AU  - Dabby R
FAU - Gorodin, S
AU  - Gorodin S
FAU - Shohat, B
AU  - Shohat B
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Austria
TA  - Arch Virol
JT  - Archives of virology
JID - 7506870
SB  - IM
MH  - Aged
MH  - Carrier State/*virology
MH  - Case-Control Studies
MH  - Cell Nucleus/virology
MH  - Cytoplasm/virology
MH  - Epithelium/virology
MH  - Female
MH  - HTLV-I Infections/*virology
MH  - Human T-lymphotropic virus 1/genetics/*isolation & purification
MH  - Humans
MH  - In Situ Hybridization
MH  - Lymphocytes/virology
MH  - Male
MH  - Mouth/virology
MH  - Paraparesis, Tropical Spastic/*virology
MH  - Therapeutic Irrigation
EDAT- 1998/06/30 00:00
MHDA- 1998/06/30 00:01
CRDT- 1998/06/30 00:00
PHST- 1998/06/30 00:00 [pubmed]
PHST- 1998/06/30 00:01 [medline]
PHST- 1998/06/30 00:00 [entrez]
AID - 10.1007/s007050050352 [doi]
PST - ppublish
SO  - Arch Virol. 1998;143(5):1029-34. doi: 10.1007/s007050050352.