PMID- 9650035
OWN - NLM
STAT- MEDLINE
DCOM- 19980904
LR  - 20190914
IS  - 0163-8343 (Print)
IS  - 0163-8343 (Linking)
VI  - 20
IP  - 3
DP  - 1998 May
TI  - Recovery and relapse in geriatric depression after treatment with antidepressants 
      and ECT in a medical-psychiatric population.
PG  - 170-4
AB  - The objective of this naturalistic, longitudinal treatment outcome study was to 
      determine relapse rates in geriatric depression following treatment with 
      antidepressants and electroconvulsive therapy in a medical-psychiatric 
      population. Thirty-nine elderly patients (average age 71 years) with unipolar 
      major depression were treated with either antidepressants (AD) or, if resistant 
      to AD treatment, ECT followed by maintenance antidepressants. Patients were 
      monitored over 18 months, and relapse rates were closely determined using the 
      Longitudinal Interval Follow-up Evaluation (LIFE) and the 21-item Hamilton 
      Depression Rating Scale. Although 90% of patients recovered from their index 
      episode of depression, relapse rates were approximately 29%. These results 
      indicate that in spite of high chances of recovery from geriatric depression, 
      intensive psychopharmacologic and psychotherapeutic strategies are needed to 
      decrease relapse rates in geriatric depression.
FAU - Stoudemire, A
AU  - Stoudemire A
AD  - Department of Psychiatry and Behavioral Sciences, Emory University School of 
      Medicine, Atlanta, Georgia, USA.
FAU - Hill, C D
AU  - Hill CD
FAU - Marquardt, M
AU  - Marquardt M
FAU - Dalton, S
AU  - Dalton S
FAU - Lewison, B J
AU  - Lewison BJ
LA  - eng
GR  - R01 MH47597/MH/NIMH NIH HHS/United States
GR  - R03 MH43549/MH/NIMH NIH HHS/United States
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Gen Hosp Psychiatry
JT  - General hospital psychiatry
JID - 7905527
RN  - 0 (Antidepressive Agents)
SB  - IM
MH  - Aged
MH  - Antidepressive Agents/*therapeutic use
MH  - Depressive Disorder, Major/diagnosis/*therapy
MH  - *Electroconvulsive Therapy
MH  - Humans
MH  - Middle Aged
MH  - Psychiatric Status Rating Scales
MH  - Recurrence
MH  - Remission Induction/methods
MH  - Treatment Outcome
EDAT- 1998/07/03 00:00
MHDA- 1998/07/03 00:01
CRDT- 1998/07/03 00:00
PHST- 1998/07/03 00:00 [pubmed]
PHST- 1998/07/03 00:01 [medline]
PHST- 1998/07/03 00:00 [entrez]
AID - S0163-8343(98)00015-2 [pii]
AID - 10.1016/s0163-8343(98)00015-2 [doi]
PST - ppublish
SO  - Gen Hosp Psychiatry. 1998 May;20(3):170-4. doi: 10.1016/s0163-8343(98)00015-2.