PMID- 9671093
OWN - NLM
STAT- MEDLINE
DCOM- 19980923
LR  - 20220321
IS  - 0014-2999 (Print)
IS  - 0014-2999 (Linking)
VI  - 349
IP  - 2-3
DP  - 1998 May 22
TI  - Melatonin facilitates short-term memory.
PG  - 159-62
AB  - The olfactory social memory test, based on the recognition of a juvenile rat by a 
      male adult rat, was used to investigate whether melatonin influences memory. 
      Intracerebroventricular (i.c.v.) injection of 1.1 nmol melatonin shortened 
      recognition time, while the melatonin ML1 receptor antagonist luzindole (1 nmol) 
      exerted the opposite effect. The facilitating influence of melatonin was 
      abolished in the presence of 0.5 nmol luzindole. The findings suggest that 
      endogenous melatonin facilitates short-term memory.
FAU - Argyriou, A
AU  - Argyriou A
AD  - Department of Pharmacology and Toxicology, University of Innsbruck, Austria.
FAU - Prast, H
AU  - Prast H
FAU - Philippu, A
AU  - Philippu A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Eur J Pharmacol
JT  - European journal of pharmacology
JID - 1254354
RN  - 0 (Receptors, Cell Surface)
RN  - 0 (Receptors, Cytoplasmic and Nuclear)
RN  - 0 (Receptors, Melatonin)
RN  - 0 (Tryptamines)
RN  - 117946-91-5 (luzindole)
RN  - JL5DK93RCL (Melatonin)
SB  - IM
MH  - Animals
MH  - Injections, Intraventricular
MH  - Male
MH  - Melatonin/*pharmacology
MH  - Memory/*drug effects
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Receptors, Cell Surface/drug effects
MH  - Receptors, Cytoplasmic and Nuclear/drug effects
MH  - Receptors, Melatonin
MH  - Social Behavior
MH  - Tryptamines/pharmacology
EDAT- 1998/07/22 00:00
MHDA- 1998/07/22 00:01
CRDT- 1998/07/22 00:00
PHST- 1998/07/22 00:00 [pubmed]
PHST- 1998/07/22 00:01 [medline]
PHST- 1998/07/22 00:00 [entrez]
AID - S0014-2999(98)00300-8 [pii]
AID - 10.1016/s0014-2999(98)00300-8 [doi]
PST - ppublish
SO  - Eur J Pharmacol. 1998 May 22;349(2-3):159-62. doi: 10.1016/s0014-2999(98)00300-8.