PMID- 9676419
OWN - NLM
STAT- MEDLINE
DCOM- 19980924
LR  - 20190826
IS  - 0302-2838 (Print)
IS  - 0302-2838 (Linking)
VI  - 34
IP  - 1
DP  - 1998
TI  - Comparison of questionnaire-based and serological screening for natural latex 
      allergy in children with neurogenic bladder dysfunction.
PG  - 79-83
AB  - OBJECTIVE: We evaluated the prevalence of sensitization to natural latex in 
      children with congenital neurogenic bladder dysfunction by patient history and 
      serological examinations. METHOD: 50 consecutive children aged from 6 months to 
      17 years were included into the study which comprised questionnaires of patient 
      and family histories, serological screening tests for common inhalational 
      allergens (CAP SX1), and determination of total serum immunoglobulin E (IgE) and 
      of latex-specific serum IgE by solid-phase immunoassays. RESULTS: 5 children had 
      a history of allergic reactions to natural latex; a history of atopic disposition 
      or allergic reactions other than to latex was present in 16 children. In 10 
      children, latex-specific IgE levels were elevated: > 0.35 kU/l; 6 out of these 10 
      children had no history of allergic reactions to latex. Elevated latex-specific 
      IgE values were statistically correlated with the number of past operations (p < 
      0.006) and a history of atopic or allergic reactions (p < 0.0067). Clean 
      intermittent catheterization, however, was not associated with an increased risk 
      of latex allergy (p = 0.408). CONCLUSION: When screening children with congenital 
      neurogenic bladder dysfunction for sensitization to natural latex, serological 
      examinations of latex-specific IgE in addition to patient history may better 
      identify patients at risk.
FAU - Zoller, G
AU  - Zoller G
AD  - Department of Urology, University of Gottingen, Germany. 
      gzoeller@med.uni-goettingen.de
FAU - Thermann, F
AU  - Thermann F
FAU - Conrad, S
AU  - Conrad S
FAU - Fuchs, T
AU  - Fuchs T
FAU - Ringert, R H
AU  - Ringert RH
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Eur Urol
JT  - European urology
JID - 7512719
RN  - 0 (Allergens)
RN  - 0 (Latex)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Allergens
MH  - Child
MH  - Child, Preschool
MH  - Humans
MH  - Hypersensitivity/complications/*diagnosis
MH  - Hypersensitivity, Immediate/complications/diagnosis
MH  - Immunoglobulin E/blood
MH  - Infant
MH  - Latex/*adverse effects/immunology
MH  - Surveys and Questionnaires
MH  - Urinary Bladder, Neurogenic/*complications
EDAT- 1998/07/24 02:07
MHDA- 2000/10/06 11:01
CRDT- 1998/07/24 02:07
PHST- 1998/07/24 02:07 [pubmed]
PHST- 2000/10/06 11:01 [medline]
PHST- 1998/07/24 02:07 [entrez]
AID - eur34079 [pii]
AID - 10.1159/000019666 [doi]
PST - ppublish
SO  - Eur Urol. 1998;34(1):79-83. doi: 10.1159/000019666.