PMID- 9677695 OWN - NLM STAT- MEDLINE DCOM- 19980814 LR - 20161018 IS - 1997-7298 (Print) IS - 1997-7298 (Linking) VI - 98 IP - 6 DP - 1998 TI - [Cerebrospinal fluid sorption in patients with heroin addiction]. PG - 32-4 AB - The sorption of cerebrospinal fluid (CSF) was attempted as a special detoxifying procedure in a group of sixty heroine addicts. CSF contents of cells, total protein, nucleic acids and interleukin-1 (IL-1), as well as acridine orange (AO) binding to CSF cells were determined before and after the procedure. The treatment provided immediate clinical improvement for 70% of the patients. Clinical effect was accompanied by decreased of CSF cells, diminished nucleic acids and protein amounts, along with increased DNA-AO binding and accumulation of IL-l. These data are interpreted in terms of intensive apoptosis of CSF cells and increased acute phase of aseptic inflammation-like events induced by the procedure of liquor sorption. FAU - Mikhailova, N G AU - Mikhailova NG FAU - Reshchikov, A M AU - Reshchikov AM FAU - Tokalov, S V AU - Tokalov SV FAU - Khanson, K P AU - Khanson KP FAU - Kornilov, N V AU - Kornilov NV FAU - Iagunov, A S AU - Iagunov AS FAU - Chukhlovin, A B AU - Chukhlovin AB LA - rus PT - Comparative Study PT - English Abstract PT - Journal Article TT - Likvorosorbtsiia u bol'nykh geroinovoi narkomaniei. PL - Russia (Federation) TA - Zh Nevrol Psikhiatr Im S S Korsakova JT - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova JID - 9712194 RN - 0 (Cerebrospinal Fluid Proteins) RN - 63231-63-0 (RNA) RN - 9007-49-2 (DNA) SB - IM MH - Cerebrospinal Fluid/*chemistry/cytology/immunology MH - Cerebrospinal Fluid Proteins/analysis MH - DNA/analysis MH - Evaluation Studies as Topic MH - Fluorescence MH - Heroin Dependence/cerebrospinal fluid/*therapy MH - Humans MH - RNA/analysis MH - Rosette Formation MH - *Sorption Detoxification EDAT- 1998/07/25 00:00 MHDA- 1998/07/25 00:01 CRDT- 1998/07/25 00:00 PHST- 1998/07/25 00:00 [pubmed] PHST- 1998/07/25 00:01 [medline] PHST- 1998/07/25 00:00 [entrez] PST - ppublish SO - Zh Nevrol Psikhiatr Im S S Korsakova. 1998;98(6):32-4.