PMID- 9681843
OWN - NLM
STAT- MEDLINE
DCOM- 19980813
LR  - 20190905
IS  - 0954-6820 (Print)
IS  - 0954-6820 (Linking)
VI  - 243
IP  - 6
DP  - 1998 Jun
TI  - Pathology of MEN-1: morphology, clinicopathologic correlations and tumour 
      development.
PG  - 455-64
AB  - Multiple endocrine neoplasia type 1 (MEN-1) is an inherited syndrome which is 
      characterized by the occurrence of neoplastic lesions in the parathyroids, the 
      pancreas, duodenum, anterior pituitary and, less commonly, also in the stomach, 
      thymus and lung. Its genetic defect has recently been identified and appears to 
      involve a new type of tumour suppressor gene called mu on chromosome 11q13. In 
      this overview, we will summarize the morphological features of the MEN-1 
      phenotype, discuss its clinicopathologic profile and prognosis and outline the 
      recent findings on the molecular pathology of this syndrome.
FAU - Komminoth, P
AU  - Komminoth P
AD  - Department of Pathology, University of Zurich, Switzerland.
FAU - Heitz, P U
AU  - Heitz PU
FAU - Kloppel, G
AU  - Kloppel G
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - J Intern Med
JT  - Journal of internal medicine
JID - 8904841
SB  - IM
MH  - Diagnosis, Differential
MH  - Humans
MH  - Multiple Endocrine Neoplasia Type 1/*diagnosis/*genetics/pathology
MH  - Prognosis
RF  - 81
EDAT- 1998/07/29 00:00
MHDA- 1998/07/29 00:01
CRDT- 1998/07/29 00:00
PHST- 1998/07/29 00:00 [pubmed]
PHST- 1998/07/29 00:01 [medline]
PHST- 1998/07/29 00:00 [entrez]
AID - 10.1046/j.1365-2796.1998.00274.x [doi]
PST - ppublish
SO  - J Intern Med. 1998 Jun;243(6):455-64. doi: 10.1046/j.1365-2796.1998.00274.x.