PMID- 9682848
OWN - NLM
STAT- MEDLINE
DCOM- 19980818
LR  - 20220330
IS  - 0003-4894 (Print)
IS  - 0003-4894 (Linking)
VI  - 107
IP  - 7
DP  - 1998 Jul
TI  - Otologic Wegener's granulomatosis with facial nerve palsy.
PG  - 555-9
AB  - Wegener's granulomatosis, characterized by necrotizing granulomas and vasculitis 
      of the respiratory tract and kidney, frequently first presents with otologic 
      symptoms. We report a case of primary otologic Wegener's granulomatosis in a 
      patient who presented with symptoms of acute otomastoiditis and associated facial 
      nerve palsy. The patient subsequently developed neuropathies of various cranial 
      nerves. The patient underwent urgent mastoidectomy with facial nerve 
      decompression. Nonspecific inflammatory disease of the mastoid mucosa delayed the 
      correct diagnosis of Wegener's granulomatosis, which was confirmed by an elevated 
      level of cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA). We 
      contrast the specificity of middle ear mucosal disease and cANCA serum levels in 
      the diagnosis of Wegener's granulomatosis.
FAU - Dagum, P
AU  - Dagum P
AD  - Division of Otolaryngology-Head and Neck Surgery, Stanford University Medical 
      Center, California, USA.
FAU - Roberson, J B Jr
AU  - Roberson JB Jr
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Ann Otol Rhinol Laryngol
JT  - The Annals of otology, rhinology, and laryngology
JID - 0407300
SB  - IM
MH  - Audiometry, Pure-Tone
MH  - Facial Paralysis/diagnosis/*etiology
MH  - Female
MH  - Granulomatosis with Polyangiitis/*complications/*diagnosis/surgery
MH  - Hearing Loss, Conductive/diagnosis/etiology
MH  - Hearing Loss, Sensorineural/diagnosis/etiology
MH  - Humans
MH  - Middle Aged
MH  - Radiography
MH  - Severity of Illness Index
MH  - Temporal Bone/*diagnostic imaging/surgery
MH  - Tympanic Membrane Perforation/etiology
EDAT- 1998/07/31 02:02
MHDA- 2001/03/28 10:01
CRDT- 1998/07/31 02:02
PHST- 1998/07/31 02:02 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1998/07/31 02:02 [entrez]
AID - 10.1177/000348949810700702 [doi]
PST - ppublish
SO  - Ann Otol Rhinol Laryngol. 1998 Jul;107(7):555-9. doi: 10.1177/000348949810700702.