PMID- 970998 OWN - NLM STAT- MEDLINE DCOM- 19761201 LR - 20190503 IS - 0003-4967 (Print) IS - 1468-2060 (Electronic) IS - 0003-4967 (Linking) VI - 35 IP - 4 DP - 1976 Aug TI - Raised serum immunoglobulin E in Wegener's granulomatosis. PG - 377-80 AB - Five patients with Wegner's granulomatosis were found to have significantly raised serum immunoglobulin E (IgE) levels. The rise in IgE was not related to the extent of clinical involvement, was not part of a generalized serum immunoglobulin rise, and was not associated with eosinophilia. Raised serum IgE may be a clue to the pathogenesis of this disease. FAU - Conn, D L AU - Conn DL FAU - Gleich, G J AU - Gleich GJ FAU - DeRemee, R A AU - DeRemee RA FAU - McDonald, T J AU - McDonald TJ LA - eng PT - Case Reports PT - Journal Article PL - England TA - Ann Rheum Dis JT - Annals of the rheumatic diseases JID - 0372355 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Aged MH - Female MH - Granulomatosis with Polyangiitis/*immunology MH - Humans MH - Immunoglobulin E/*analysis MH - Male MH - Middle Aged PMC - PMC1007400 EDAT- 1976/08/01 00:00 MHDA- 1976/08/01 00:01 PMCR- 1979/08/01 CRDT- 1976/08/01 00:00 PHST- 1976/08/01 00:00 [pubmed] PHST- 1976/08/01 00:01 [medline] PHST- 1976/08/01 00:00 [entrez] PHST- 1979/08/01 00:00 [pmc-release] AID - 10.1136/ard.35.4.377 [doi] PST - ppublish SO - Ann Rheum Dis. 1976 Aug;35(4):377-80. doi: 10.1136/ard.35.4.377.