PMID- 9711884
OWN - NLM
STAT- MEDLINE
DCOM- 19981006
LR  - 20190516
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 37
IP  - 7
DP  - 1998 Jul
TI  - Methylprednisolone pulse therapy in two clinical types of crescentic 
      glomerulonephritis.
PG  - 585-91
AB  - To clarify the effectiveness of methylprednisolone pulse therapy on crescentic 
      glomerulonephritis (CresGN), data of 46 patients was retrospectively studied. 
      According to the slope of reciprocals of serum creatinine (s-Cr) the patients 
      were divided into acute and insidious types, and each type was further divided 
      into pulse (P) and conventional (C) therapy groups. In group C, s-Cr improved 
      more frequently in the acute type (8/10) than in the insidious type (1/9, 
      p<0.05), and the renal survival rate was somewhat higher in the former (p=0.09). 
      In the acute type there was no difference in the improvement rate of s-Cr between 
      the two therapy groups, whereas in the insidious type, the improvement rate was 
      higher in group P (9/15) than in group C (1/9, p<0.05) and the renal survival 
      rate was higher in the former (p<0.01). These results suggest that 
      methylprednisolone pulse therapy may be highly effective for the insidious type 
      of CresGN.
FAU - Takeda, S
AU  - Takeda S
AD  - Internal Medicine of Kurobe City Hospital, Toyama.
FAU - Kida, H
AU  - Kida H
FAU - Yokoyama, H
AU  - Yokoyama H
FAU - Takazakura, E
AU  - Takazakura E
FAU - Kobayashi, K
AU  - Kobayashi K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Glucocorticoids)
RN  - AYI8EX34EU (Creatinine)
RN  - X4W7ZR7023 (Methylprednisolone)
SB  - IM
CIN - Intern Med. 1998 Aug;37(8):651. PMID: 9745848
MH  - Acute Disease
MH  - Adult
MH  - Aged
MH  - Creatinine/blood
MH  - Female
MH  - Glomerulonephritis/blood/*drug therapy/physiopathology
MH  - Glucocorticoids/*administration & dosage
MH  - Humans
MH  - Kidney/drug effects/physiopathology
MH  - Male
MH  - Methylprednisolone/*administration & dosage
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 1998/08/26 00:00
MHDA- 1998/08/26 00:01
CRDT- 1998/08/26 00:00
PHST- 1998/08/26 00:00 [pubmed]
PHST- 1998/08/26 00:01 [medline]
PHST- 1998/08/26 00:00 [entrez]
AID - 10.2169/internalmedicine.37.585 [doi]
PST - ppublish
SO  - Intern Med. 1998 Jul;37(7):585-91. doi: 10.2169/internalmedicine.37.585.