PMID- 9714001
OWN - NLM
STAT- MEDLINE
DCOM- 19980930
LR  - 20191024
IS  - 1045-2257 (Print)
IS  - 1045-2257 (Linking)
VI  - 23
IP  - 1
DP  - 1998 Sep
TI  - Identification of a 100-kb region of common allelic loss on chromosome bands 
      10q25-q26 in human endometrial cancer.
PG  - 74-7
AB  - In human endometrial cancer, we have previously identified a 790-kb region of 
      common allelic loss in chromosome bands 10q25-q26, flanked by D10S587 and 
      D10S1723. We constructed a contig covering the entire deleted region using YACs, 
      PACs, and BACs. Five overlapping cosmid clones derived from YAC clones completely 
      covered the entire deleted region: its size was estimated to be no larger than 
      200 kb. We further performed two-color fluorescence in situ hybridization (FISH) 
      analysis to confirm the deletion and narrowed down the deleted region to 100 kb 
      or less; it was covered by three overlapping cosmid clones that were included in 
      one BAC clone. Restriction endonuclease mapping identified a region in which 
      NotI, SalI, SmaI, and Xhol were clustered, suggesting the possible existence of a 
      CpG island.
FAU - Yamakawa, H
AU  - Yamakawa H
AD  - Department of Molecular Pathology, Tohoku University School of Medicine, Sendai, 
      Japan.
FAU - Nagase, S
AU  - Nagase S
FAU - Yuki, M
AU  - Yuki M
FAU - Shiwaku, H O
AU  - Shiwaku HO
FAU - Furukawa, T
AU  - Furukawa T
FAU - Yoshinaga, K
AU  - Yoshinaga K
FAU - Soeda, E
AU  - Soeda E
FAU - Hoshi, M
AU  - Hoshi M
FAU - Hayashi, Y
AU  - Hayashi Y
FAU - Sato, S
AU  - Sato S
FAU - Yajima, A
AU  - Yajima A
FAU - Horii, A
AU  - Horii A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genes Chromosomes Cancer
JT  - Genes, chromosomes & cancer
JID - 9007329
SB  - IM
MH  - Chromosome Banding
MH  - Chromosome Fragility
MH  - Chromosomes, Artificial, Yeast
MH  - Chromosomes, Human, Pair 10/*genetics
MH  - Cloning, Molecular
MH  - Endometrial Neoplasms/*genetics
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Loss of Heterozygosity
MH  - Restriction Mapping
EDAT- 1998/08/26 02:24
MHDA- 2000/06/20 09:00
CRDT- 1998/08/26 02:24
PHST- 1998/08/26 02:24 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1998/08/26 02:24 [entrez]
AID - 10.1002/(SICI)1098-2264(199809)23:1<74::AID-GCC12>3.0.CO;2-E [pii]
AID - 10.1002/(sici)1098-2264(199809)23:1<74::aid-gcc12>3.0.co;2-e [doi]
PST - ppublish
SO  - Genes Chromosomes Cancer. 1998 Sep;23(1):74-7. doi: 
      10.1002/(sici)1098-2264(199809)23:1<74::aid-gcc12>3.0.co;2-e.