PMID- 9718481 OWN - NLM STAT- MEDLINE DCOM- 19981026 LR - 20170214 IS - 0023-6772 (Print) IS - 0023-6772 (Linking) VI - 32 IP - 3 DP - 1998 Jul TI - Thoracic electrical bioimpedance: a non-invasive measure of cardiac output for porcine research. PG - 324-9 AB - A comparison of two techniques for measuring cardiac output, thermodilution (TD) and thoracic electrical bioimpedance (TEB), was undertaken in a porcine model. Eight anaesthetized large white pigs were studied. A total of 436 paired measurements were performed over a range of cardiac outputs from 1.7 to 15.1 l/min as measured by thermodilution. The Pearson product moment correlation coefficient was r = 0.963 with P < 0.001. Analysis by Bland and Altman statistics revealed a mean difference (bias) of -0.02 l/min and the limits of agreement were +/- 1.6 l/min, similar to figures found in human comparative studies. These results confirm that thoracic electrical bioimpedance is a valid method of measuring cardiac output in pigs. It has significant advantages compared to thermodilution, in particular it is cheap, simple to use, non-invasive and provides continuous data. FAU - Broomhead, C J AU - Broomhead CJ AD - Sir Henry Souttar Research Laboratories, Royal Hospitals Trust, The Royal London Hospital, London, UK. FAU - Wright, S J AU - Wright SJ FAU - Kiff, K M AU - Kiff KM FAU - Withington, P S AU - Withington PS LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Lab Anim JT - Laboratory animals JID - 0112725 SB - IM MH - Animals MH - *Cardiac Output MH - *Cardiography, Impedance MH - Female MH - Swine/*physiology MH - Thermodilution EDAT- 1998/08/27 00:00 MHDA- 1998/08/27 00:01 CRDT- 1998/08/27 00:00 PHST- 1998/08/27 00:00 [pubmed] PHST- 1998/08/27 00:01 [medline] PHST- 1998/08/27 00:00 [entrez] AID - 10.1258/002367798780559266 [doi] PST - ppublish SO - Lab Anim. 1998 Jul;32(3):324-9. doi: 10.1258/002367798780559266.