PMID- 9732771
OWN - NLM
STAT- MEDLINE
DCOM- 19980923
LR  - 20190831
IS  - 0750-7658 (Print)
IS  - 0750-7658 (Linking)
VI  - 16
IP  - 3
DP  - 1997
TI  - [Malignant hyperthermia and appendicular sepsis. Can they be differentiated 
      during surgical procedure?].
PG  - 234-8
AB  - OBJECTIVE: To assess the possibility to differentiate clinically intraoperative 
      malignant hyperthermia (MH) and sepsis. STUDY DESIGN: Comparative retrospective 
      study of clinical cases. PATIENTS: Sixteen patients operated on for acute 
      appendicitis and developing clinical signs of MH confirmed or not by in vitro 
      caffeine halothane contracture tests (IVCT). METHOD: To isolate the patients' 
      characteristics with regard to the diagnosis of sepsis and MH crisis. To compare 
      both groups of clinical features with results of IVCT. RESULTS: The diagnosis of 
      MH sensitivity has been excluded in ten hyperthermic patients and confirmed in 
      four others with IVCT. No correlation was existing between the importance of 
      perioperative sepsis, MH features and IVTC results. CONCLUSIONS: This study 
      confirmed the difficulty to differentiate clinically MH and sepsis during 
      surgery. Considering the severe outcome of MH crisis, it is recommended to start 
      the specific therapy even in case of appendicular sepsis.
FAU - Strecker, G
AU  - Strecker G
AD  - Departement d'anesthesie-reanimation chirurgicale I, hopital R-Salengro, Lille, 
      France.
FAU - Adnet, P
AU  - Adnet P
FAU - Forget, A P
AU  - Forget AP
FAU - Krivosic-Horber, R
AU  - Krivosic-Horber R
LA  - fre
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - Hyperthermie maligne et etat infectieux d'origine appendiculaire. Peut-on les 
      differencier en cours d'intervention?
PL  - France
TA  - Ann Fr Anesth Reanim
JT  - Annales francaises d'anesthesie et de reanimation
JID - 8213275
RN  - 0 (Muscle Relaxants, Central)
RN  - F64QU97QCR (Dantrolene)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Appendicitis/*complications
MH  - Child
MH  - Dantrolene/therapeutic use
MH  - Diagnosis, Differential
MH  - Female
MH  - Fever/etiology
MH  - Humans
MH  - *Intraoperative Complications
MH  - Male
MH  - *Malignant Hyperthermia/diagnosis/drug therapy/mortality
MH  - Muscle Relaxants, Central/therapeutic use
MH  - Retrospective Studies
MH  - Sepsis/*diagnosis/etiology
MH  - Treatment Outcome
EDAT- 1997/01/01 00:00
MHDA- 1998/09/11 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1998/09/11 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - S0750765897864076 [pii]
AID - 10.1016/s0750-7658(97)86407-6 [doi]
PST - ppublish
SO  - Ann Fr Anesth Reanim. 1997;16(3):234-8. doi: 10.1016/s0750-7658(97)86407-6.